ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000135144 DTX1 H. sapiens SDL Slorth 0.980774 View
ENSG00000097007 ABL1 ENSG00000128512 DOCK4 H. sapiens SDL Slorth 0.980709 View
ENSG00000097007 ABL1 ENSG00000105063 PPP6R1 H. sapiens SDL Slorth 0.98068 View
ENSG00000097007 ABL1 ENSG00000115685 PPP1R7 H. sapiens SDL Slorth 0.98067 View
ENSG00000097007 ABL1 ENSG00000143878 RHOB H. sapiens SDL Slorth 0.980661 View
ENSG00000061918 GUCY1B3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.980649 View
ENSG00000097007 ABL1 ENSG00000163655 GMPS H. sapiens SDL Slorth 0.980645 View
ENSG00000097007 ABL1 ENSG00000115355 CCDC88A H. sapiens SDL Slorth 0.980635 View
ENSG00000097007 ABL1 ENSG00000120705 ETF1 H. sapiens SDL Slorth 0.980624 View
ENSG00000097007 ABL1 ENSG00000149503 INCENP H. sapiens SDL Slorth 0.980583 View
ENSG00000097007 ABL1 ENSG00000138756 BMP2K H. sapiens SDL Slorth 0.980572 View
ENSG00000097007 ABL1 ENSG00000198648 STK39 H. sapiens SDL Slorth 0.980562 View
ENSG00000097007 ABL1 ENSG00000134333 LDHA H. sapiens SDL Slorth 0.980559 View
ENSG00000097007 ABL1 ENSG00000182872 RBM10 H. sapiens SDL Slorth 0.980523 View
ENSG00000067141 NEO1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.980521 View
ENSG00000097007 ABL1 ENSG00000111206 FOXM1 H. sapiens SDL Slorth 0.980516 View
ENSG00000097007 ABL1 ENSG00000148516 ZEB1 H. sapiens SDL Slorth 0.980469 View
ENSG00000097007 ABL1 ENSG00000171109 MFN1 H. sapiens SDL Slorth 0.980421 View
ENSG00000097007 ABL1 ENSG00000198947 DMD H. sapiens SDL Slorth 0.980404 View
ENSG00000097007 ABL1 ENSG00000155846 PPARGC1B H. sapiens SDL Slorth 0.980381 View
ENSG00000097007 ABL1 ENSG00000114737 CISH H. sapiens SDL Slorth 0.980356 View
ENSG00000097007 ABL1 ENSG00000120149 MSX2 H. sapiens SDL Slorth 0.980325 View
ENSG00000097007 ABL1 ENSG00000141380 SS18 H. sapiens SDL Slorth 0.980322 View
ENSG00000097007 ABL1 ENSG00000187522 HSPA14 H. sapiens SDL Slorth 0.98028 View
ENSG00000097007 ABL1 ENSG00000102898 NUTF2 H. sapiens SDL Slorth 0.980275 View
ENSG00000097007 ABL1 ENSG00000115221 ITGB6 H. sapiens SDL Slorth 0.980259 View
ENSG00000083857 FAT1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.980244 View
ENSG00000097007 ABL1 ENSG00000124795 DEK H. sapiens SDL Slorth 0.980235 View
ENSG00000097007 ABL1 ENSG00000100614 PPM1A H. sapiens SDL Slorth 0.980195 View
ENSG00000097007 ABL1 ENSG00000110777 POU2AF1 H. sapiens SDL Slorth 0.98019 View
ENSG00000097007 ABL1 ENSG00000136504 KAT7 H. sapiens SDL Slorth 0.980187 View
ENSG00000097007 ABL1 ENSG00000149930 TAOK2 H. sapiens SDL Slorth 0.980177 View
ENSG00000097007 ABL1 ENSG00000180176 TH H. sapiens SDL Slorth 0.980174 View
ENSG00000097007 ABL1 ENSG00000175203 DCTN2 H. sapiens SDL Slorth 0.98014 View
ENSG00000097007 ABL1 ENSG00000130956 HABP4 H. sapiens SDL Slorth 0.979996 View
ENSG00000097007 ABL1 ENSG00000254505 CHMP4A H. sapiens SDL Slorth 0.979988 View
ENSG00000097007 ABL1 ENSG00000173848 NET1 H. sapiens SDL Slorth 0.979945 View
ENSG00000097007 ABL1 ENSG00000197111 PCBP2 H. sapiens SDL Slorth 0.979942 View
ENSG00000097007 ABL1 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.979863 View
ENSG00000097007 ABL1 ENSG00000158022 TRIM63 H. sapiens SDL Slorth 0.979856 View