ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000100503 NIN H. sapiens SDL Slorth 0.977942 View
ENSG00000097007 ABL1 ENSG00000138029 HADHB H. sapiens SDL Slorth 0.97794 View
ENSG00000097007 ABL1 ENSG00000152684 PELO H. sapiens SDL Slorth 0.977864 View
ENSG00000097007 ABL1 ENSG00000165637 VDAC2 H. sapiens SDL Slorth 0.97785 View
ENSG00000097007 ABL1 ENSG00000157873 TNFRSF14 H. sapiens SDL Slorth 0.977802 View
ENSG00000097007 ABL1 ENSG00000108094 CUL2 H. sapiens SDL Slorth 0.97778 View
ENSG00000097007 ABL1 ENSG00000112576 CCND3 H. sapiens SDL Slorth 0.977777 View
ENSG00000097007 ABL1 ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.977767 View
ENSG00000097007 ABL1 ENSG00000169862 CTNND2 H. sapiens SDL Slorth 0.97776 View
ENSG00000097007 ABL1 ENSG00000107807 TLX1 H. sapiens SDL Slorth 0.977725 View
ENSG00000097007 ABL1 ENSG00000221914 PPP2R2A H. sapiens SDL Slorth 0.977722 View
ENSG00000005339 CREBBP ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977703 View
ENSG00000097007 ABL1 ENSG00000105197 TIMM50 H. sapiens SDL Slorth 0.977696 View
ENSG00000097007 ABL1 ENSG00000149925 ALDOA H. sapiens SDL Slorth 0.977693 View
ENSG00000097007 ABL1 ENSG00000111716 LDHB H. sapiens SDL Slorth 0.977693 View
ENSG00000082146 STRADB ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977689 View
ENSG00000097007 ABL1 ENSG00000131507 NDFIP1 H. sapiens SDL Slorth 0.977688 View
ENSG00000090889 KIF4A ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977664 View
ENSG00000005882 PDK2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977664 View
ENSG00000090432 MUL1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977657 View
ENSG00000097007 ABL1 ENSG00000185359 HGS H. sapiens SSL Slorth 0.977647 View
ENSG00000064489 BORCS8-MEF2B ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977632 View
ENSG00000097007 ABL1 ENSG00000143171 RXRG H. sapiens SDL Slorth 0.977598 View
ENSG00000087085 ACHE ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977596 View
ENSG00000097007 ABL1 ENSG00000174903 RAB1B H. sapiens SDL Slorth 0.977592 View
ENSG00000097007 ABL1 ENSG00000141556 TBCD H. sapiens SDL Slorth 0.977584 View
ENSG00000097007 ABL1 ENSG00000151729 SLC25A4 H. sapiens SDL Slorth 0.97758 View
ENSG00000097007 ABL1 ENSG00000113387 SUB1 H. sapiens SDL Slorth 0.977578 View
ENSG00000097007 ABL1 ENSG00000213079 SCAF8 H. sapiens SDL Slorth 0.977531 View
ENSG00000091831 ESR1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977512 View
ENSG00000097007 ABL1 ENSG00000144668 ITGA9 H. sapiens SDL Slorth 0.977499 View
ENSG00000097007 ABL1 ENSG00000173209 AHSA2 H. sapiens SDL Slorth 0.977498 View
ENSG00000097007 ABL1 ENSG00000138613 APH1B H. sapiens SDL Slorth 0.977488 View
ENSG00000080345 RIF1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977487 View
ENSG00000097007 ABL1 ENSG00000183814 LIN9 H. sapiens SDL Slorth 0.977483 View
ENSG00000097007 ABL1 ENSG00000160867 FGFR4 H. sapiens SDL Slorth 0.97746 View
ENSG00000097007 ABL1 ENSG00000146457 WTAP H. sapiens SDL Slorth 0.977456 View
ENSG00000097007 ABL1 ENSG00000155097 ATP6V1C1 H. sapiens SDL Slorth 0.977442 View
ENSG00000097007 ABL1 ENSG00000130764 LRRC47 H. sapiens SDL Slorth 0.977425 View
ENSG00000097007 ABL1 ENSG00000255112 CHMP1B H. sapiens SDL Slorth 0.977406 View