SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000111087 GLI1 H. sapiens SDL Slorth 0.928053 View
ENSG00000096717 SIRT1 ENSG00000113569 NUP155 H. sapiens SSL Slorth 0.927985 View
ENSG00000096717 SIRT1 ENSG00000182872 RBM10 H. sapiens SSL Slorth 0.927881 View
ENSG00000096717 SIRT1 ENSG00000213024 NUP62 H. sapiens SDL Slorth 0.92781 View
ENSG00000096717 SIRT1 ENSG00000119912 IDE H. sapiens SSL Slorth 0.927803 View
ENSG00000096717 SIRT1 ENSG00000131759 RARA H. sapiens SDL Slorth 0.927711 View
ENSG00000096717 SIRT1 ENSG00000175197 DDIT3 H. sapiens SDL Slorth 0.927681 View
ENSG00000096717 SIRT1 ENSG00000175792 RUVBL1 H. sapiens SDL Slorth 0.927654 View
ENSG00000096717 SIRT1 ENSG00000103653 CSK H. sapiens SDL Slorth 0.927596 View
ENSG00000096717 SIRT1 ENSG00000102900 NUP93 H. sapiens SDL Slorth 0.927587 View
ENSG00000096717 SIRT1 ENSG00000159210 SNF8 H. sapiens SDL Slorth 0.927534 View
ENSG00000096717 SIRT1 ENSG00000101751 POLI H. sapiens SSL Slorth 0.927511 View
ENSG00000096717 SIRT1 ENSG00000115053 NCL H. sapiens SDL Slorth 0.927498 View
ENSG00000096717 SIRT1 ENSG00000125630 POLR1B H. sapiens SDL Slorth 0.927493 View
ENSG00000096717 SIRT1 ENSG00000172939 OXSR1 H. sapiens SDL Slorth 0.927474 View
ENSG00000096717 SIRT1 ENSG00000254087 LYN H. sapiens SDL Slorth 0.927399 View
ENSG00000096717 SIRT1 ENSG00000136273 HUS1 H. sapiens SSL Slorth 0.927395 View
ENSG00000096717 SIRT1 ENSG00000122545 SEPT7 H. sapiens SDL Slorth 0.927289 View
ENSG00000096717 SIRT1 ENSG00000112079 STK38 H. sapiens SSL Slorth 0.927279 View
ENSG00000096717 SIRT1 ENSG00000105723 GSK3A H. sapiens SSL Slorth 0.92723 View
ENSG00000096717 SIRT1 ENSG00000147010 SH3KBP1 H. sapiens SSL Slorth 0.927206 View
ENSG00000096717 SIRT1 ENSG00000114166 KAT2B H. sapiens SDL Slorth 0.927197 View
ENSG00000096717 SIRT1 ENSG00000167670 CHAF1A H. sapiens SSL Slorth 0.92719 View
ENSG00000096717 SIRT1 ENSG00000167553 TUBA1C H. sapiens SSL Slorth 0.927167 View
ENSG00000096717 SIRT1 ENSG00000187098 MITF H. sapiens SSL Slorth 0.927127 View
ENSG00000096717 SIRT1 ENSG00000169710 FASN H. sapiens SSL Slorth 0.927093 View
ENSG00000096717 SIRT1 ENSG00000198373 WWP2 H. sapiens SSL Slorth 0.927056 View
ENSG00000096717 SIRT1 ENSG00000175054 ATR H. sapiens SDL Slorth 0.927046 View
ENSG00000096717 SIRT1 ENSG00000129521 EGLN3 H. sapiens SDL Slorth 0.927037 View
ENSG00000096717 SIRT1 ENSG00000170836 PPM1D H. sapiens SDL Slorth 0.927035 View
ENSG00000070476 ZXDC ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.926965 View
ENSG00000096717 SIRT1 ENSG00000104408 EIF3E H. sapiens SDL Slorth 0.926939 View
ENSG00000096717 SIRT1 ENSG00000101003 GINS1 H. sapiens SDL Slorth 0.92692 View
ENSG00000096717 SIRT1 ENSG00000165119 HNRNPK H. sapiens SDL Slorth 0.926908 View
ENSG00000096717 SIRT1 ENSG00000102038 SMARCA1 H. sapiens SDL Slorth 0.926862 View
ENSG00000096717 SIRT1 ENSG00000167985 SDHAF2 H. sapiens SDL Slorth 0.926847 View
ENSG00000096717 SIRT1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.926733 View
ENSG00000096717 SIRT1 ENSG00000123908 AGO2 H. sapiens SSL Slorth 0.926725 View
ENSG00000096717 SIRT1 ENSG00000140332 TLE3 H. sapiens SDL Slorth 0.926724 View
ENSG00000096717 SIRT1 ENSG00000124795 DEK H. sapiens SSL Slorth 0.926682 View