SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000101665 SMAD7 H. sapiens SDL Slorth 0.923137 View
ENSG00000096717 SIRT1 ENSG00000119335 SET H. sapiens SDL Slorth 0.923132 View
ENSG00000096717 SIRT1 ENSG00000107643 MAPK8 H. sapiens SDL Slorth 0.923125 View
ENSG00000096717 SIRT1 ENSG00000158402 CDC25C H. sapiens SDL Slorth 0.923065 View
ENSG00000096717 SIRT1 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.92306 View
ENSG00000096717 SIRT1 ENSG00000132383 RPA1 H. sapiens SDL Slorth 0.923048 View
ENSG00000096717 SIRT1 ENSG00000104856 RELB H. sapiens SSL Slorth 0.922902 View
ENSG00000071051 NCK2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.922884 View
ENSG00000096717 SIRT1 ENSG00000113387 SUB1 H. sapiens SDL Slorth 0.922843 View
ENSG00000096717 SIRT1 ENSG00000183072 NKX2-5 H. sapiens SDL Slorth 0.922769 View
ENSG00000096717 SIRT1 ENSG00000145907 G3BP1 H. sapiens SSL Slorth 0.922668 View
ENSG00000096717 SIRT1 ENSG00000106462 EZH2 H. sapiens SDL Slorth 0.922649 View
ENSG00000096717 SIRT1 ENSG00000133119 RFC3 H. sapiens SDL Slorth 0.922562 View
ENSG00000096717 SIRT1 ENSG00000134899 ERCC5 H. sapiens SDL Slorth 0.922512 View
ENSG00000096717 SIRT1 ENSG00000166855 CLPX H. sapiens SSL Slorth 0.922277 View
ENSG00000096717 SIRT1 ENSG00000269858 EGLN2 H. sapiens SDL Slorth 0.922272 View
ENSG00000096717 SIRT1 ENSG00000138398 PPIG H. sapiens SSL Slorth 0.922257 View
ENSG00000096717 SIRT1 ENSG00000123349 PFDN5 H. sapiens SSL Slorth 0.922227 View
ENSG00000096717 SIRT1 ENSG00000198231 DDX42 H. sapiens SSL Slorth 0.92222 View
ENSG00000096717 SIRT1 ENSG00000167258 CDK12 H. sapiens SSL Slorth 0.922178 View
ENSG00000070159 PTPN3 ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.922095 View
ENSG00000006451 RALA ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.922028 View
ENSG00000096717 SIRT1 ENSG00000164754 RAD21 H. sapiens SSL Slorth 0.921971 View
ENSG00000096717 SIRT1 ENSG00000125818 PSMF1 H. sapiens SDL Slorth 0.921953 View
ENSG00000096717 SIRT1 ENSG00000245848 CEBPA H. sapiens SDL Slorth 0.921908 View
ENSG00000096717 SIRT1 ENSG00000156269 NAA11 H. sapiens SSL Slorth 0.921814 View
ENSG00000096717 SIRT1 ENSG00000135903 PAX3 H. sapiens SSL Slorth 0.921798 View
ENSG00000096717 SIRT1 ENSG00000121481 RNF2 H. sapiens SDL Slorth 0.921774 View
ENSG00000096717 SIRT1 ENSG00000172845 SP3 H. sapiens SSL Slorth 0.921736 View
ENSG00000096717 SIRT1 ENSG00000117450 PRDX1 H. sapiens SDL Slorth 0.921732 View
ENSG00000096717 SIRT1 ENSG00000130560 UBAC1 H. sapiens SSL Slorth 0.921626 View
ENSG00000096717 SIRT1 ENSG00000132356 PRKAA1 H. sapiens SSL Slorth 0.92161 View
ENSG00000093009 CDC45 ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.921589 View
ENSG00000096717 SIRT1 ENSG00000157557 ETS2 H. sapiens SDL Slorth 0.921426 View
ENSG00000096717 SIRT1 ENSG00000117399 CDC20 H. sapiens SDL Slorth 0.92142 View
ENSG00000096717 SIRT1 ENSG00000198836 OPA1 H. sapiens SDL Slorth 0.921322 View
ENSG00000096717 SIRT1 ENSG00000171223 JUNB H. sapiens SDL Slorth 0.921311 View
ENSG00000096717 SIRT1 ENSG00000135424 ITGA7 H. sapiens SDL Slorth 0.921306 View
ENSG00000096717 SIRT1 ENSG00000130522 JUND H. sapiens SDL Slorth 0.921254 View
ENSG00000096717 SIRT1 ENSG00000131773 KHDRBS3 H. sapiens SSL Slorth 0.921222 View