SIRT1

ENSG00000096717 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0002039 p53 binding
GO:0003714 transcription corepressor activity
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0017136 NAD-dependent histone deacetylase activity
GO:0019213 deacetylase activity
GO:0019899 enzyme binding
GO:0033558 protein deacetylase activity
GO:0034979 NAD-dependent protein deacetylase activity
GO:0035257 nuclear hormone receptor binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043398 HLH domain binding
GO:0043425 bHLH transcription factor binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0051019 mitogen-activated protein kinase binding
GO:0070403 NAD+ binding
GO:1990254 keratin filament binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
HST1 S. cerevisiae
SIR2 S. cerevisiae
sir-2.1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000096717 SIRT1 ENSG00000101146 RAE1 H. sapiens SSL Slorth 0.917004 View
ENSG00000096717 SIRT1 ENSG00000154229 PRKCA H. sapiens SDL Slorth 0.916953 View
ENSG00000096717 SIRT1 ENSG00000170734 POLH H. sapiens SDL Slorth 0.916912 View
ENSG00000096717 SIRT1 ENSG00000204388 HSPA1B H. sapiens SSL Slorth 0.916911 View
ENSG00000096717 SIRT1 ENSG00000183943 PRKX H. sapiens SDL Slorth 0.916895 View
ENSG00000096717 SIRT1 ENSG00000130764 LRRC47 H. sapiens SDL Slorth 0.916864 View
ENSG00000096717 SIRT1 ENSG00000177731 FLII H. sapiens SSL Slorth 0.916803 View
ENSG00000096717 SIRT1 ENSG00000108654 DDX5 H. sapiens SDL Slorth 0.91676 View
ENSG00000096717 SIRT1 ENSG00000156475 PPP2R2B H. sapiens SDL Slorth 0.916665 View
ENSG00000096717 SIRT1 ENSG00000182621 PLCB1 H. sapiens SDL Slorth 0.916609 View
ENSG00000096717 SIRT1 ENSG00000130332 LSM7 H. sapiens SSL Slorth 0.916583 View
ENSG00000096717 SIRT1 ENSG00000170345 FOS H. sapiens SDL Slorth 0.91639 View
ENSG00000096717 SIRT1 ENSG00000109471 IL2 H. sapiens SDL Slorth 0.916381 View
ENSG00000096717 SIRT1 ENSG00000105011 ASF1B H. sapiens SDL Slorth 0.916267 View
ENSG00000096717 SIRT1 ENSG00000113916 BCL6 H. sapiens SSL Slorth 0.91611 View
ENSG00000096717 SIRT1 ENSG00000116833 NR5A2 H. sapiens SSL Slorth 0.916047 View
ENSG00000096717 SIRT1 ENSG00000196498 NCOR2 H. sapiens SDL Slorth 0.91604 View
ENSG00000096717 SIRT1 ENSG00000124571 XPO5 H. sapiens SDL Slorth 0.916038 View
ENSG00000096717 SIRT1 ENSG00000136826 KLF4 H. sapiens SSL Slorth 0.915998 View
ENSG00000096717 SIRT1 ENSG00000100297 MCM5 H. sapiens SDL Slorth 0.915943 View
ENSG00000096717 SIRT1 ENSG00000187735 TCEA1 H. sapiens SDL Slorth 0.915943 View
ENSG00000096717 SIRT1 ENSG00000109062 SLC9A3R1 H. sapiens SDL Slorth 0.915771 View
ENSG00000096717 SIRT1 ENSG00000157020 SEC13 H. sapiens SSL Slorth 0.915682 View
ENSG00000096717 SIRT1 ENSG00000112640 PPP2R5D H. sapiens SDL Slorth 0.915669 View
ENSG00000096717 SIRT1 ENSG00000159461 AMFR H. sapiens SDL Slorth 0.91551 View
ENSG00000096717 SIRT1 ENSG00000100644 HIF1A H. sapiens SDL Slorth 0.915444 View
ENSG00000096717 SIRT1 ENSG00000163625 WDFY3 H. sapiens SDL Slorth 0.915358 View
ENSG00000096717 SIRT1 ENSG00000109685 WHSC1 H. sapiens SSL Slorth 0.915311 View
ENSG00000096717 SIRT1 ENSG00000136931 NR5A1 H. sapiens SSL Slorth 0.915271 View
ENSG00000096717 SIRT1 ENSG00000134574 DDB2 H. sapiens SDL Slorth 0.915232 View
ENSG00000071242 RPS6KA2 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.915228 View
ENSG00000096717 SIRT1 ENSG00000135521 LTV1 H. sapiens SSL Slorth 0.915219 View
ENSG00000096717 SIRT1 ENSG00000225830 ERCC6 H. sapiens SDL Slorth 0.915209 View
ENSG00000083520 DIS3 ENSG00000096717 SIRT1 H. sapiens SSL Slorth 0.915189 View
ENSG00000096717 SIRT1 ENSG00000169564 PCBP1 H. sapiens SDL Slorth 0.91515 View
ENSG00000096717 SIRT1 ENSG00000171723 GPHN H. sapiens SDL Slorth 0.915142 View
ENSG00000096717 SIRT1 ENSG00000188603 CLN3 H. sapiens SDL Slorth 0.914974 View
ENSG00000096717 SIRT1 ENSG00000197728 RPS26 H. sapiens SDL Slorth 0.914954 View
ENSG00000096717 SIRT1 ENSG00000135144 DTX1 H. sapiens SSL Slorth 0.914949 View
ENSG00000077312 SNRPA ENSG00000096717 SIRT1 H. sapiens SDL Slorth 0.914946 View