PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000183814 LIN9 H. sapiens SSL Slorth 0.818748 View
ENSG00000143799 PARP1 ENSG00000180228 PRKRA H. sapiens SSL Slorth 0.818696 View
ENSG00000143799 PARP1 ENSG00000157404 KIT H. sapiens SSL Slorth 0.818459 View
ENSG00000143799 PARP1 ENSG00000173145 NOC3L H. sapiens SSL Slorth 0.817856 View
ENSG00000143799 PARP1 ENSG00000147416 ATP6V1B2 H. sapiens SSL Slorth 0.817846 View
ENSG00000143799 PARP1 ENSG00000241553 ARPC4 H. sapiens SSL Slorth 0.817767 View
ENSG00000143799 PARP1 ENSG00000148229 POLE3 H. sapiens SSL Slorth 0.817762 View
ENSG00000280548 FBL ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.817393 View
ENSG00000143799 PARP1 ENSG00000170525 PFKFB3 H. sapiens SSL Slorth 0.817294 View
ENSG00000143799 PARP1 ENSG00000173801 JUP H. sapiens SSL Slorth 0.817042 View
ENSG00000143799 PARP1 ENSG00000178295 GEN1 H. sapiens SSL Slorth 0.816724 View
ENSG00000143799 PARP1 ENSG00000204388 HSPA1B H. sapiens SSL Slorth 0.816395 View
ENSG00000143799 PARP1 ENSG00000165731 RET H. sapiens SSL Slorth 0.816191 View
ENSG00000143799 PARP1 ENSG00000143878 RHOB H. sapiens SSL Slorth 0.815777 View
ENSG00000143799 PARP1 ENSG00000198648 STK39 H. sapiens SSL Slorth 0.815272 View
ENSG00000143799 PARP1 ENSG00000168090 COPS6 H. sapiens SSL Slorth 0.814241 View
ENSG00000143799 PARP1 ENSG00000175354 PTPN2 H. sapiens SSL Slorth 0.814231 View
ENSG00000143799 PARP1 ENSG00000176014 TUBB6 H. sapiens SSL Slorth 0.814135 View
ENSG00000134954 ETS1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.814126 View
ENSG00000141968 VAV1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.813993 View
ENSG00000101336 HCK ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.813018 View
ENSG00000143799 PARP1 ENSG00000146872 TLK2 H. sapiens SSL Slorth 0.812781 View
ENSG00000143799 PARP1 ENSG00000184110 EIF3C H. sapiens SSL Slorth 0.812607 View
ENSG00000143799 PARP1 ENSG00000177426 TGIF1 H. sapiens SSL Slorth 0.812338 View
ENSG00000053372 MRTO4 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.812225 View
ENSG00000143799 PARP1 ENSG00000184182 UBE2F H. sapiens SSL Slorth 0.811627 View
ENSG00000143799 PARP1 ENSG00000163904 SENP2 H. sapiens SSL Slorth 0.811416 View
ENSG00000142192 APP ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.811373 View
ENSG00000143799 PARP1 ENSG00000147955 SIGMAR1 H. sapiens SSL Slorth 0.811365 View
ENSG00000075785 RAB7A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.811281 View
ENSG00000143799 PARP1 ENSG00000184675 AMER1 H. sapiens SSL Slorth 0.811232 View
ENSG00000143799 PARP1 ENSG00000255150 EID3 H. sapiens SSL Slorth 0.810941 View
ENSG00000130826 DKC1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.810862 View
ENSG00000143799 PARP1 ENSG00000185344 ATP6V0A2 H. sapiens SSL Slorth 0.810764 View
ENSG00000143799 PARP1 ENSG00000172936 MYD88 H. sapiens SSL Slorth 0.810654 View
ENSG00000143799 PARP1 ENSG00000156587 UBE2L6 H. sapiens SSL Slorth 0.81047 View
ENSG00000126524 SBDS ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.81043 View
ENSG00000119707 RBM25 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.810085 View
ENSG00000122566 HNRNPA2B1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.81001 View
ENSG00000143799 PARP1 ENSG00000151148 UBE3B H. sapiens SSL Slorth 0.809955 View