PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000172340 SUCLG2 H. sapiens SSL Slorth 0.792011 View
ENSG00000105329 TGFB1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.791815 View
ENSG00000143799 PARP1 ENSG00000177613 CSTF2T H. sapiens SSL Slorth 0.791441 View
ENSG00000143799 PARP1 ENSG00000182621 PLCB1 H. sapiens SSL Slorth 0.791283 View
ENSG00000074266 EED ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.79068 View
ENSG00000143799 PARP1 ENSG00000242173 ARHGDIG H. sapiens SSL Slorth 0.79062 View
ENSG00000143799 PARP1 ENSG00000197837 HIST4H4 H. sapiens SSL Slorth 0.789978 View
ENSG00000143799 PARP1 ENSG00000163629 PTPN13 H. sapiens SSL Slorth 0.789662 View
ENSG00000101460 MAP1LC3A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.789609 View
ENSG00000143799 PARP1 ENSG00000159377 PSMB4 H. sapiens SSL Slorth 0.789385 View
ENSG00000143799 PARP1 ENSG00000173334 TRIB1 H. sapiens SSL Slorth 0.789314 View
ENSG00000143799 PARP1 ENSG00000155980 KIF5A H. sapiens SSL Slorth 0.788982 View
ENSG00000089737 DDX24 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.788904 View
ENSG00000071051 NCK2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.788101 View
ENSG00000143799 PARP1 ENSG00000172795 DCP2 H. sapiens SSL Slorth 0.787804 View
ENSG00000143799 PARP1 ENSG00000151748 SAV1 H. sapiens SSL Slorth 0.78754 View
ENSG00000114573 ATP6V1A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.787511 View
ENSG00000138663 COPS4 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.787504 View
ENSG00000143799 PARP1 ENSG00000196911 KPNA5 H. sapiens SSL Slorth 0.787334 View
ENSG00000143799 PARP1 ENSG00000170606 HSPA4 H. sapiens SSL Slorth 0.785939 View
ENSG00000143799 PARP1 ENSG00000197905 TEAD4 H. sapiens SSL Slorth 0.785873 View
ENSG00000143799 PARP1 ENSG00000160007 ARHGAP35 H. sapiens SSL Slorth 0.785627 View
ENSG00000143799 PARP1 ENSG00000171720 HDAC3 H. sapiens SSL Slorth 0.78561 View
ENSG00000143799 PARP1 ENSG00000175305 CCNE2 H. sapiens SSL Slorth 0.785498 View
ENSG00000117360 PRPF3 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.785139 View
ENSG00000143799 PARP1 ENSG00000196459 TRAPPC2 H. sapiens SSL Slorth 0.785111 View
ENSG00000143799 PARP1 ENSG00000163466 ARPC2 H. sapiens SSL Slorth 0.78465 View
ENSG00000143799 PARP1 ENSG00000181789 COPG1 H. sapiens SSL Slorth 0.784515 View
ENSG00000139343 SNRPF ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.784311 View
ENSG00000143799 PARP1 ENSG00000167985 SDHAF2 H. sapiens SSL Slorth 0.783887 View
ENSG00000143799 PARP1 ENSG00000164171 ITGA2 H. sapiens SSL Slorth 0.783699 View
ENSG00000143799 PARP1 ENSG00000211456 SACM1L H. sapiens SSL Slorth 0.783683 View
ENSG00000143799 PARP1 ENSG00000147065 MSN H. sapiens SSL Slorth 0.783637 View
ENSG00000143799 PARP1 ENSG00000147573 TRIM55 H. sapiens SSL Slorth 0.783293 View
ENSG00000143799 PARP1 ENSG00000157168 NRG1 H. sapiens SSL Slorth 0.783067 View
ENSG00000143799 PARP1 ENSG00000183020 AP2A2 H. sapiens SSL Slorth 0.782932 View
ENSG00000143799 PARP1 ENSG00000158545 ZC3H18 H. sapiens SSL Slorth 0.782862 View
ENSG00000116473 RAP1A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.782133 View
ENSG00000143799 PARP1 ENSG00000185624 P4HB H. sapiens SSL Slorth 0.781671 View
ENSG00000128739 SNRPN ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.781585 View