PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000124181 PLCG1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.854035 View
ENSG00000143093 STRIP1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.853681 View
ENSG00000143799 PARP1 ENSG00000186350 RXRA H. sapiens SSL Slorth 0.853465 View
ENSG00000143799 PARP1 ENSG00000171094 ALK H. sapiens SSL Slorth 0.853451 View
ENSG00000110955 ATP5B ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.853345 View
ENSG00000143799 PARP1 ENSG00000196961 AP2A1 H. sapiens SSL Slorth 0.853078 View
ENSG00000143799 PARP1 ENSG00000173726 TOMM20 H. sapiens SSL Slorth 0.853031 View
ENSG00000143799 PARP1 ENSG00000186868 MAPT H. sapiens SSL Slorth 0.852789 View
ENSG00000073969 NSF ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.851969 View
ENSG00000143799 PARP1 ENSG00000172732 MUS81 H. sapiens SSL Slorth 0.85192 View
ENSG00000143799 PARP1 ENSG00000164056 SPRY1 H. sapiens SSL Slorth 0.851831 View
ENSG00000143799 PARP1 ENSG00000175634 RPS6KB2 H. sapiens SSL Slorth 0.850328 View
ENSG00000069329 VPS35 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.849215 View
ENSG00000112578 BYSL ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.848129 View
ENSG00000143799 PARP1 ENSG00000185379 RAD51D H. sapiens SSL Slorth 0.848102 View
ENSG00000140396 NCOA2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.847981 View
ENSG00000134987 WDR36 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.847828 View
ENSG00000143799 PARP1 ENSG00000148516 ZEB1 H. sapiens SSL Slorth 0.84762 View
ENSG00000001167 NFYA ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.847006 View
ENSG00000067560 RHOA ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.84692 View
ENSG00000143799 PARP1 ENSG00000183853 KIRREL H. sapiens SSL Slorth 0.846917 View
ENSG00000143799 PARP1 ENSG00000161202 DVL3 H. sapiens SSL Slorth 0.845978 View
ENSG00000143799 PARP1 ENSG00000149923 PPP4C H. sapiens SSL Slorth 0.845622 View
ENSG00000143799 PARP1 ENSG00000156976 EIF4A2 H. sapiens SSL Slorth 0.845588 View
ENSG00000143799 PARP1 ENSG00000145555 MYO10 H. sapiens SSL Slorth 0.845233 View
ENSG00000143799 PARP1 ENSG00000177105 RHOG H. sapiens SSL Slorth 0.844943 View
ENSG00000143799 PARP1 ENSG00000153071 DAB2 H. sapiens SSL Slorth 0.844454 View
ENSG00000103363 TCEB2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.844393 View
ENSG00000130699 TAF4 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.844342 View
ENSG00000100201 DDX17 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.844191 View
ENSG00000143799 PARP1 ENSG00000176444 CLK2 H. sapiens SSL Slorth 0.844115 View
ENSG00000104980 TIMM44 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.842785 View
ENSG00000143799 PARP1 ENSG00000172409 CLP1 H. sapiens SSL Slorth 0.841667 View
ENSG00000143799 PARP1 ENSG00000170248 PDCD6IP H. sapiens SSL Slorth 0.841641 View
ENSG00000143799 PARP1 ENSG00000189079 ARID2 H. sapiens SSL Slorth 0.841243 View
ENSG00000107404 DVL1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.840787 View
ENSG00000143799 PARP1 ENSG00000170759 KIF5B H. sapiens SSL Slorth 0.840653 View
ENSG00000143799 PARP1 ENSG00000151247 EIF4E H. sapiens SSL Slorth 0.840349 View
ENSG00000143799 PARP1 ENSG00000171148 TADA3 H. sapiens SSL Slorth 0.840239 View
ENSG00000143799 PARP1 ENSG00000179348 GATA2 H. sapiens SSL Slorth 0.839849 View