PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000155660 PDIA4 H. sapiens SSL Slorth 0.839791 View
ENSG00000143799 PARP1 ENSG00000198947 DMD H. sapiens SSL Slorth 0.839339 View
ENSG00000095015 MAP3K1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.839077 View
ENSG00000143799 PARP1 ENSG00000211455 STK38L H. sapiens SSL Slorth 0.838773 View
ENSG00000115524 SF3B1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.838239 View
ENSG00000113141 IK ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.838203 View
ENSG00000143799 PARP1 ENSG00000204390 HSPA1L H. sapiens SSL Slorth 0.837982 View
ENSG00000143799 PARP1 ENSG00000187522 HSPA14 H. sapiens SSL Slorth 0.837982 View
ENSG00000143799 PARP1 ENSG00000169744 LDB2 H. sapiens SSL Slorth 0.837779 View
ENSG00000122565 CBX3 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.837336 View
ENSG00000143799 PARP1 ENSG00000168209 DDIT4 H. sapiens SSL Slorth 0.837202 View
ENSG00000119318 RAD23B ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.836771 View
ENSG00000069399 BCL3 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.836427 View
ENSG00000143799 PARP1 ENSG00000151422 FER H. sapiens SSL Slorth 0.835495 View
ENSG00000143799 PARP1 ENSG00000155849 ELMO1 H. sapiens SSL Slorth 0.835264 View
ENSG00000143799 PARP1 ENSG00000198898 CAPZA2 H. sapiens SSL Slorth 0.835258 View
ENSG00000080839 RBL1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.835211 View
ENSG00000143799 PARP1 ENSG00000177688 SUMO4 H. sapiens SSL Slorth 0.834709 View
ENSG00000133119 RFC3 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.834563 View
ENSG00000143799 PARP1 ENSG00000168214 RBPJ H. sapiens SSL Slorth 0.834269 View
ENSG00000143799 PARP1 ENSG00000179091 CYC1 H. sapiens SSL Slorth 0.834211 View
ENSG00000115053 NCL ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.834022 View
ENSG00000143799 PARP1 ENSG00000197312 DDI2 H. sapiens SSL Slorth 0.83381 View
ENSG00000143799 PARP1 ENSG00000198873 GRK5 H. sapiens SSL Slorth 0.833303 View
ENSG00000136100 VPS36 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.833228 View
ENSG00000124207 CSE1L ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.833135 View
ENSG00000143799 PARP1 ENSG00000163516 ANKZF1 H. sapiens SSL Slorth 0.832795 View
ENSG00000143799 PARP1 ENSG00000213281 NRAS H. sapiens SSL Slorth 0.832625 View
ENSG00000143799 PARP1 ENSG00000155868 MED7 H. sapiens SSL Slorth 0.831844 View
ENSG00000143799 PARP1 ENSG00000156970 BUB1B H. sapiens SSL Slorth 0.831355 View
ENSG00000103496 STX4 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.831169 View
ENSG00000143799 PARP1 ENSG00000188229 TUBB4B H. sapiens SSL Slorth 0.830495 View
ENSG00000143799 PARP1 ENSG00000175203 DCTN2 H. sapiens SSL Slorth 0.830369 View
ENSG00000143799 PARP1 ENSG00000165410 CFL2 H. sapiens SSL Slorth 0.830146 View
ENSG00000143799 PARP1 ENSG00000177879 AP3S1 H. sapiens SSL Slorth 0.829732 View
ENSG00000143799 PARP1 ENSG00000151694 ADAM17 H. sapiens SSL Slorth 0.829671 View
ENSG00000143799 PARP1 ENSG00000196839 ADA H. sapiens SSL Slorth 0.82936 View
ENSG00000143799 PARP1 ENSG00000163527 STT3B H. sapiens SSL Slorth 0.829271 View
ENSG00000101109 STK4 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.829061 View
ENSG00000143799 PARP1 ENSG00000159593 NAE1 H. sapiens SSL Slorth 0.828623 View