PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101343 CRNKL1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.801338 View
ENSG00000143799 PARP1 ENSG00000166974 MAPRE2 H. sapiens SSL Slorth 0.801288 View
ENSG00000143799 PARP1 ENSG00000197780 TAF13 H. sapiens SSL Slorth 0.801037 View
ENSG00000143799 PARP1 ENSG00000220205 VAMP2 H. sapiens SSL Slorth 0.800486 View
ENSG00000129083 COPB1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.800089 View
ENSG00000143799 PARP1 ENSG00000197498 RPF2 H. sapiens SSL Slorth 0.799607 View
ENSG00000143799 PARP1 ENSG00000173402 DAG1 H. sapiens SSL Slorth 0.799507 View
ENSG00000143799 PARP1 ENSG00000159352 PSMD4 H. sapiens SSL Slorth 0.799073 View
ENSG00000130811 EIF3G ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.798943 View
ENSG00000143799 PARP1 ENSG00000187266 EPOR H. sapiens SSL Slorth 0.798808 View
ENSG00000111581 NUP107 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.798671 View
ENSG00000143799 PARP1 ENSG00000147669 POLR2K H. sapiens SSL Slorth 0.798565 View
ENSG00000143799 PARP1 ENSG00000159251 ACTC1 H. sapiens SSL Slorth 0.798358 View
ENSG00000143799 PARP1 ENSG00000183943 PRKX H. sapiens SSL Slorth 0.798101 View
ENSG00000143799 PARP1 ENSG00000169696 ASPSCR1 H. sapiens SSL Slorth 0.798085 View
ENSG00000143799 PARP1 ENSG00000149100 EIF3M H. sapiens SSL Slorth 0.797933 View
ENSG00000125630 POLR1B ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.797904 View
ENSG00000104408 EIF3E ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.797725 View
ENSG00000143799 PARP1 ENSG00000198399 ITSN2 H. sapiens SSL Slorth 0.79762 View
ENSG00000143799 PARP1 ENSG00000163577 EIF5A2 H. sapiens SSL Slorth 0.79762 View
ENSG00000143799 PARP1 ENSG00000178573 MAF H. sapiens SSL Slorth 0.797496 View
ENSG00000124164 VAPB ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.797405 View
ENSG00000143799 PARP1 ENSG00000242247 ARFGAP3 H. sapiens SSL Slorth 0.797267 View
ENSG00000143799 PARP1 ENSG00000166266 CUL5 H. sapiens SSL Slorth 0.797256 View
ENSG00000143799 PARP1 ENSG00000166869 CHP2 H. sapiens SSL Slorth 0.796883 View
ENSG00000105402 NAPA ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.796428 View
ENSG00000143799 PARP1 ENSG00000203879 GDI1 H. sapiens SSL Slorth 0.795626 View
ENSG00000143799 PARP1 ENSG00000162733 DDR2 H. sapiens SSL Slorth 0.795559 View
ENSG00000143799 PARP1 ENSG00000156299 TIAM1 H. sapiens SSL Slorth 0.795432 View
ENSG00000122728 TAF1L ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.795185 View
ENSG00000143799 PARP1 ENSG00000247077 PGAM5 H. sapiens SSL Slorth 0.794277 View
ENSG00000143799 PARP1 ENSG00000170881 RNF139 H. sapiens SSL Slorth 0.794195 View
ENSG00000143799 PARP1 ENSG00000166407 LMO1 H. sapiens SSL Slorth 0.794129 View
ENSG00000117713 ARID1A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.79381 View
ENSG00000143799 PARP1 ENSG00000144283 PKP4 H. sapiens SSL Slorth 0.793804 View
ENSG00000100347 SAMM50 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.79363 View
ENSG00000143799 PARP1 ENSG00000184575 XPOT H. sapiens SSL Slorth 0.793627 View
ENSG00000108587 GOSR1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.793257 View
ENSG00000143799 PARP1 ENSG00000262814 MRPL12 H. sapiens SSL Slorth 0.792203 View
ENSG00000143437 ARNT ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.792153 View