ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000179218 CALR H. sapiens SSL Slorth 0.921934 View
ENSG00000097007 ABL1 ENSG00000152137 HSPB8 H. sapiens SSL Slorth 0.921909 View
ENSG00000097007 ABL1 ENSG00000113595 TRIM23 H. sapiens SSL Slorth 0.921889 View
ENSG00000097007 ABL1 ENSG00000100307 CBX7 H. sapiens SSL Slorth 0.921871 View
ENSG00000097007 ABL1 ENSG00000247596 TWF2 H. sapiens SDL Slorth 0.921827 View
ENSG00000097007 ABL1 ENSG00000100034 PPM1F H. sapiens SSL Slorth 0.921774 View
ENSG00000072062 PRKACA ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.921723 View
ENSG00000097007 ABL1 ENSG00000100823 APEX1 H. sapiens SDL Slorth 0.921711 View
ENSG00000097007 ABL1 ENSG00000173726 TOMM20 H. sapiens SSL Slorth 0.921685 View
ENSG00000097007 ABL1 ENSG00000138802 SEC24B H. sapiens SSL Slorth 0.921672 View
ENSG00000061938 TNK2 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.921617 View
ENSG00000097007 ABL1 ENSG00000111725 PRKAB1 H. sapiens SSL Slorth 0.921608 View
ENSG00000097007 ABL1 ENSG00000105443 CYTH2 H. sapiens SDL Slorth 0.921574 View
ENSG00000097007 ABL1 ENSG00000254995 STX16-NPEPL1 H. sapiens SDL Slorth 0.921541 View
ENSG00000097007 ABL1 ENSG00000140455 USP3 H. sapiens SSL Slorth 0.921419 View
ENSG00000097007 ABL1 ENSG00000097033 SH3GLB1 H. sapiens SSL Slorth 0.921404 View
ENSG00000097007 ABL1 ENSG00000166855 CLPX H. sapiens SSL Slorth 0.921403 View
ENSG00000097007 ABL1 ENSG00000147044 CASK H. sapiens SDL Slorth 0.921388 View
ENSG00000097007 ABL1 ENSG00000175054 ATR H. sapiens SSL Slorth 0.921366 View
ENSG00000097007 ABL1 ENSG00000167004 PDIA3 H. sapiens SSL Slorth 0.92136 View
ENSG00000097007 ABL1 ENSG00000133104 SPG20 H. sapiens SSL Slorth 0.921301 View
ENSG00000097007 ABL1 ENSG00000221983 UBA52 H. sapiens SDL Slorth 0.921286 View
ENSG00000092010 PSME1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.92124 View
ENSG00000097007 ABL1 ENSG00000141252 VPS53 H. sapiens SSL Slorth 0.921233 View
ENSG00000097007 ABL1 ENSG00000124535 WRNIP1 H. sapiens SDL Slorth 0.921232 View
ENSG00000097007 ABL1 ENSG00000182117 NOP10 H. sapiens SSL Slorth 0.921044 View
ENSG00000097007 ABL1 ENSG00000101003 GINS1 H. sapiens SSL Slorth 0.920849 View
ENSG00000004897 CDC27 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.920818 View
ENSG00000097007 ABL1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.920748 View
ENSG00000077721 UBE2A ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.920516 View
ENSG00000097007 ABL1 ENSG00000099364 FBXL19 H. sapiens SDL Slorth 0.920468 View
ENSG00000097007 ABL1 ENSG00000171132 PRKCE H. sapiens SDL Slorth 0.920466 View
ENSG00000097007 ABL1 ENSG00000173020 GRK2 H. sapiens SSL Slorth 0.920433 View
ENSG00000097007 ABL1 ENSG00000128513 POT1 H. sapiens SSL Slorth 0.920379 View
ENSG00000097007 ABL1 ENSG00000182621 PLCB1 H. sapiens SDL Slorth 0.920336 View
ENSG00000097007 ABL1 ENSG00000150593 PDCD4 H. sapiens SDL Slorth 0.920273 View
ENSG00000097007 ABL1 ENSG00000187446 CHP1 H. sapiens SSL Slorth 0.920271 View
ENSG00000097007 ABL1 ENSG00000107105 ELAVL2 H. sapiens SSL Slorth 0.920157 View
ENSG00000097007 ABL1 ENSG00000145734 BDP1 H. sapiens SDL Slorth 0.92015 View
ENSG00000092621 PHGDH ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.92007 View