ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000087586 AURKA ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.918983 View
ENSG00000097007 ABL1 ENSG00000182606 TRAK1 H. sapiens SSL Slorth 0.918964 View
ENSG00000097007 ABL1 ENSG00000144852 NR1I2 H. sapiens SSL Slorth 0.918964 View
ENSG00000097007 ABL1 ENSG00000116604 MEF2D H. sapiens SDL Slorth 0.91895 View
ENSG00000097007 ABL1 ENSG00000100393 EP300 H. sapiens SDL Slorth 0.918908 View
ENSG00000050820 BCAR1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.918902 View
ENSG00000097007 ABL1 ENSG00000138663 COPS4 H. sapiens SSL Slorth 0.91888 View
ENSG00000097007 ABL1 ENSG00000170004 CHD3 H. sapiens SDL Slorth 0.918833 View
ENSG00000097007 ABL1 ENSG00000187735 TCEA1 H. sapiens SDL Slorth 0.918749 View
ENSG00000097007 ABL1 ENSG00000183520 UTP11 H. sapiens SSL Slorth 0.918717 View
ENSG00000097007 ABL1 ENSG00000107295 SH3GL2 H. sapiens SSL Slorth 0.918635 View
ENSG00000097007 ABL1 ENSG00000131899 LLGL1 H. sapiens SSL Slorth 0.918538 View
ENSG00000097007 ABL1 ENSG00000166888 STAT6 H. sapiens SSL Slorth 0.918476 View
ENSG00000097007 ABL1 ENSG00000127527 EPS15L1 H. sapiens SSL Slorth 0.91846 View
ENSG00000097007 ABL1 ENSG00000101336 HCK H. sapiens SSL Slorth 0.918437 View
ENSG00000097007 ABL1 ENSG00000107581 EIF3A H. sapiens SDL Slorth 0.91828 View
ENSG00000097007 ABL1 ENSG00000119718 EIF2B2 H. sapiens SSL Slorth 0.918261 View
ENSG00000097007 ABL1 ENSG00000196866 HIST1H2AD H. sapiens SSL Slorth 0.918248 View
ENSG00000097007 ABL1 ENSG00000135829 DHX9 H. sapiens SDL Slorth 0.918246 View
ENSG00000097007 ABL1 ENSG00000113575 PPP2CA H. sapiens SDL Slorth 0.918243 View
ENSG00000097007 ABL1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.918221 View
ENSG00000097007 ABL1 ENSG00000141384 TAF4B H. sapiens SSL Slorth 0.918185 View
ENSG00000097007 ABL1 ENSG00000175518 UBQLNL H. sapiens SDL Slorth 0.918076 View
ENSG00000097007 ABL1 ENSG00000260914 RP11-343C2.11 H. sapiens SDL Slorth 0.918076 View
ENSG00000097007 ABL1 ENSG00000139631 CSAD H. sapiens SDL Slorth 0.918076 View
ENSG00000097007 ABL1 ENSG00000131504 DIAPH1 H. sapiens SSL Slorth 0.917872 View
ENSG00000097007 ABL1 ENSG00000174775 HRAS H. sapiens SSL Slorth 0.917741 View
ENSG00000097007 ABL1 ENSG00000198825 INPP5F H. sapiens SDL Slorth 0.917594 View
ENSG00000097007 ABL1 ENSG00000171634 BPTF H. sapiens SDL Slorth 0.917579 View
ENSG00000072694 FCGR2B ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.917562 View
ENSG00000097007 ABL1 ENSG00000107404 DVL1 H. sapiens SDL Slorth 0.917553 View
ENSG00000097007 ABL1 ENSG00000116039 ATP6V1B1 H. sapiens SSL Slorth 0.917507 View
ENSG00000097007 ABL1 ENSG00000182481 KPNA2 H. sapiens SSL Slorth 0.917498 View
ENSG00000097007 ABL1 ENSG00000111300 NAA25 H. sapiens SSL Slorth 0.91748 View
ENSG00000097007 ABL1 ENSG00000100632 ERH H. sapiens SDL Slorth 0.917293 View
ENSG00000097007 ABL1 ENSG00000179262 RAD23A H. sapiens SDL Slorth 0.917234 View
ENSG00000097007 ABL1 ENSG00000133056 PIK3C2B H. sapiens SSL Slorth 0.917002 View
ENSG00000097007 ABL1 ENSG00000148660 CAMK2G H. sapiens SSL Slorth 0.916918 View
ENSG00000097007 ABL1 ENSG00000139343 SNRPF H. sapiens SSL Slorth 0.916764 View
ENSG00000097007 ABL1 ENSG00000186350 RXRA H. sapiens SSL Slorth 0.916751 View