ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000172493 AFF1 H. sapiens SDL Slorth 0.914548 View
ENSG00000097007 ABL1 ENSG00000138029 HADHB H. sapiens SSL Slorth 0.914491 View
ENSG00000095015 MAP3K1 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.914481 View
ENSG00000097007 ABL1 ENSG00000143507 DUSP10 H. sapiens SSL Slorth 0.914439 View
ENSG00000082898 XPO1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.914367 View
ENSG00000097007 ABL1 ENSG00000196419 XRCC6 H. sapiens SDL Slorth 0.914343 View
ENSG00000097007 ABL1 ENSG00000142864 SERBP1 H. sapiens SDL Slorth 0.914268 View
ENSG00000097007 ABL1 ENSG00000133639 BTG1 H. sapiens SSL Slorth 0.914186 View
ENSG00000097007 ABL1 ENSG00000130985 UBA1 H. sapiens SDL Slorth 0.914043 View
ENSG00000097007 ABL1 ENSG00000122958 VPS26A H. sapiens SSL Slorth 0.914025 View
ENSG00000097007 ABL1 ENSG00000197548 ATG7 H. sapiens SSL Slorth 0.914019 View
ENSG00000097007 ABL1 ENSG00000170312 CDK1 H. sapiens SDL Slorth 0.914015 View
ENSG00000012983 MAP4K5 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.913905 View
ENSG00000097007 ABL1 ENSG00000118689 FOXO3 H. sapiens SDL Slorth 0.913903 View
ENSG00000090376 IRAK3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.913761 View
ENSG00000097007 ABL1 ENSG00000184575 XPOT H. sapiens SSL Slorth 0.913747 View
ENSG00000097007 ABL1 ENSG00000173207 CKS1B H. sapiens SSL Slorth 0.913704 View
ENSG00000097007 ABL1 ENSG00000099800 TIMM13 H. sapiens SSL Slorth 0.913444 View
ENSG00000097007 ABL1 ENSG00000100749 VRK1 H. sapiens SSL Slorth 0.913309 View
ENSG00000097007 ABL1 ENSG00000107643 MAPK8 H. sapiens SDL Slorth 0.912852 View
ENSG00000097007 ABL1 ENSG00000167216 KATNAL2 H. sapiens SDL Slorth 0.912804 View
ENSG00000055609 KMT2C ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.912787 View
ENSG00000097007 ABL1 ENSG00000154710 RABGEF1 H. sapiens SDL Slorth 0.912778 View
ENSG00000097007 ABL1 ENSG00000106799 TGFBR1 H. sapiens SDL Slorth 0.912775 View
ENSG00000097007 ABL1 ENSG00000111602 TIMELESS H. sapiens SSL Slorth 0.912773 View
ENSG00000097007 ABL1 ENSG00000166484 MAPK7 H. sapiens SSL Slorth 0.912736 View
ENSG00000097007 ABL1 ENSG00000123143 PKN1 H. sapiens SSL Slorth 0.912723 View
ENSG00000097007 ABL1 ENSG00000163110 PDLIM5 H. sapiens SSL Slorth 0.912693 View
ENSG00000089157 RPLP0 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.912681 View
ENSG00000097007 ABL1 ENSG00000100644 HIF1A H. sapiens SSL Slorth 0.912637 View
ENSG00000097007 ABL1 ENSG00000183853 KIRREL H. sapiens SSL Slorth 0.912612 View
ENSG00000097007 ABL1 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.9126 View
ENSG00000097007 ABL1 ENSG00000171105 INSR H. sapiens SDL Slorth 0.912587 View
ENSG00000097007 ABL1 ENSG00000100351 GRAP2 H. sapiens SSL Slorth 0.912504 View
ENSG00000097007 ABL1 ENSG00000111206 FOXM1 H. sapiens SSL Slorth 0.912469 View
ENSG00000084072 PPIE ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.912461 View
ENSG00000097007 ABL1 ENSG00000108384 RAD51C H. sapiens SDL Slorth 0.912429 View
ENSG00000097007 ABL1 ENSG00000106803 SEC61B H. sapiens SSL Slorth 0.912406 View
ENSG00000097007 ABL1 ENSG00000140600 SH3GL3 H. sapiens SDL Slorth 0.912363 View
ENSG00000070010 UFD1L ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.912331 View