ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000126215 XRCC3 H. sapiens SDL Slorth 0.904609 View
ENSG00000097007 ABL1 ENSG00000151148 UBE3B H. sapiens SSL Slorth 0.90459 View
ENSG00000097007 ABL1 ENSG00000125733 TRIP10 H. sapiens SSL Slorth 0.904485 View
ENSG00000097007 ABL1 ENSG00000127022 CANX H. sapiens SDL Slorth 0.90444 View
ENSG00000097007 ABL1 ENSG00000119139 TJP2 H. sapiens SSL Slorth 0.904382 View
ENSG00000097007 ABL1 ENSG00000140396 NCOA2 H. sapiens SSL Slorth 0.904301 View
ENSG00000007944 MYLIP ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.904113 View
ENSG00000097007 ABL1 ENSG00000151694 ADAM17 H. sapiens SSL Slorth 0.903964 View
ENSG00000097007 ABL1 ENSG00000111361 EIF2B1 H. sapiens SSL Slorth 0.903887 View
ENSG00000097007 ABL1 ENSG00000197153 HIST1H3J H. sapiens SDL Slorth 0.903861 View
ENSG00000072518 MARK2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.903852 View
ENSG00000097007 ABL1 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.903845 View
ENSG00000097007 ABL1 ENSG00000099817 POLR2E H. sapiens SSL Slorth 0.903828 View
ENSG00000097007 ABL1 ENSG00000110719 TCIRG1 H. sapiens SSL Slorth 0.90366 View
ENSG00000097007 ABL1 ENSG00000204217 BMPR2 H. sapiens SDL Slorth 0.903492 View
ENSG00000097007 ABL1 ENSG00000184787 UBE2G2 H. sapiens SSL Slorth 0.90349 View
ENSG00000097007 ABL1 ENSG00000183814 LIN9 H. sapiens SSL Slorth 0.903461 View
ENSG00000097007 ABL1 ENSG00000198400 NTRK1 H. sapiens SSL Slorth 0.903459 View
ENSG00000097007 ABL1 ENSG00000181449 SOX2 H. sapiens SDL Slorth 0.903426 View
ENSG00000097007 ABL1 ENSG00000184432 COPB2 H. sapiens SSL Slorth 0.903403 View
ENSG00000097007 ABL1 ENSG00000134250 NOTCH2 H. sapiens SSL Slorth 0.903388 View
ENSG00000068654 POLR1A ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.903307 View
ENSG00000097007 ABL1 ENSG00000165169 DYNLT3 H. sapiens SDL Slorth 0.903293 View
ENSG00000061273 HDAC7 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.903208 View
ENSG00000069869 NEDD4 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.903149 View
ENSG00000097007 ABL1 ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.903078 View
ENSG00000097007 ABL1 ENSG00000198088 NUP62CL H. sapiens SDL Slorth 0.903076 View
ENSG00000097007 ABL1 ENSG00000139613 SMARCC2 H. sapiens SSL Slorth 0.902984 View
ENSG00000097007 ABL1 ENSG00000115464 USP34 H. sapiens SSL Slorth 0.902925 View
ENSG00000039068 CDH1 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.902834 View
ENSG00000097007 ABL1 ENSG00000138032 PPM1B H. sapiens SSL Slorth 0.902674 View
ENSG00000077312 SNRPA ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.902668 View
ENSG00000097007 ABL1 ENSG00000100345 MYH9 H. sapiens SDL Slorth 0.902599 View
ENSG00000097007 ABL1 ENSG00000121022 COPS5 H. sapiens SSL Slorth 0.902575 View
ENSG00000097007 ABL1 ENSG00000132388 UBE2G1 H. sapiens SSL Slorth 0.902553 View
ENSG00000097007 ABL1 ENSG00000147050 KDM6A H. sapiens SSL Slorth 0.902496 View
ENSG00000097007 ABL1 ENSG00000160293 VAV2 H. sapiens SSL Slorth 0.902479 View
ENSG00000097007 ABL1 ENSG00000140941 MAP1LC3B H. sapiens SSL Slorth 0.902411 View
ENSG00000097007 ABL1 ENSG00000196296 ATP2A1 H. sapiens SSL Slorth 0.9024 View
ENSG00000097007 ABL1 ENSG00000109118 PHF12 H. sapiens SDL Slorth 0.902385 View