ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000114742 WDR48 H. sapiens SSL Slorth 0.923468 View
ENSG00000097007 ABL1 ENSG00000156269 NAA11 H. sapiens SSL Slorth 0.923463 View
ENSG00000097007 ABL1 ENSG00000169375 SIN3A H. sapiens SDL Slorth 0.923406 View
ENSG00000097007 ABL1 ENSG00000159259 CHAF1B H. sapiens SSL Slorth 0.923395 View
ENSG00000097007 ABL1 ENSG00000099797 TECR H. sapiens SDL Slorth 0.923374 View
ENSG00000097007 ABL1 ENSG00000108055 SMC3 H. sapiens SSL Slorth 0.923365 View
ENSG00000097007 ABL1 ENSG00000111450 STX2 H. sapiens SDL Slorth 0.923348 View
ENSG00000097007 ABL1 ENSG00000241553 ARPC4 H. sapiens SSL Slorth 0.923325 View
ENSG00000097007 ABL1 ENSG00000172939 OXSR1 H. sapiens SDL Slorth 0.923306 View
ENSG00000096384 HSP90AB1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.923207 View
ENSG00000097007 ABL1 ENSG00000134686 PHC2 H. sapiens SDL Slorth 0.923165 View
ENSG00000097007 ABL1 ENSG00000099901 RANBP1 H. sapiens SSL Slorth 0.923152 View
ENSG00000084764 MAPRE3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.923141 View
ENSG00000097007 ABL1 ENSG00000100387 RBX1 H. sapiens SDL Slorth 0.923108 View
ENSG00000097007 ABL1 ENSG00000105963 ADAP1 H. sapiens SSL Slorth 0.923103 View
ENSG00000097007 ABL1 ENSG00000161960 EIF4A1 H. sapiens SDL Slorth 0.923039 View
ENSG00000097007 ABL1 ENSG00000101811 CSTF2 H. sapiens SSL Slorth 0.922898 View
ENSG00000097007 ABL1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.922835 View
ENSG00000085832 EPS15 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.922723 View
ENSG00000080503 SMARCA2 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.922705 View
ENSG00000097007 ABL1 ENSG00000168397 ATG4B H. sapiens SSL Slorth 0.92268 View
ENSG00000097007 ABL1 ENSG00000148341 SH3GLB2 H. sapiens SSL Slorth 0.92266 View
ENSG00000096696 DSP ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.92265 View
ENSG00000097007 ABL1 ENSG00000164171 ITGA2 H. sapiens SSL Slorth 0.922629 View
ENSG00000097007 ABL1 ENSG00000255112 CHMP1B H. sapiens SSL Slorth 0.922544 View
ENSG00000097007 ABL1 ENSG00000145604 SKP2 H. sapiens SDL Slorth 0.922406 View
ENSG00000097007 ABL1 ENSG00000185787 MORF4L1 H. sapiens SSL Slorth 0.922404 View
ENSG00000070831 CDC42 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.922387 View
ENSG00000097007 ABL1 ENSG00000132646 PCNA H. sapiens SDL Slorth 0.922228 View
ENSG00000097007 ABL1 ENSG00000166266 CUL5 H. sapiens SSL Slorth 0.922228 View
ENSG00000097007 ABL1 ENSG00000109111 SUPT6H H. sapiens SSL Slorth 0.922219 View
ENSG00000097007 ABL1 ENSG00000120500 ARR3 H. sapiens SDL Slorth 0.922183 View
ENSG00000097007 ABL1 ENSG00000196611 MMP1 H. sapiens SDL Slorth 0.922155 View
ENSG00000097007 ABL1 ENSG00000136352 NKX2-1 H. sapiens SSL Slorth 0.922068 View
ENSG00000097007 ABL1 ENSG00000221823 PPP3R1 H. sapiens SSL Slorth 0.922067 View
ENSG00000036672 USP2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.921995 View
ENSG00000005007 UPF1 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.921986 View
ENSG00000097007 ABL1 ENSG00000132768 DPH2 H. sapiens SSL Slorth 0.921969 View
ENSG00000097007 ABL1 ENSG00000117461 PIK3R3 H. sapiens SDL Slorth 0.92194 View
ENSG00000067560 RHOA ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.921938 View