ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000183495 EP400 H. sapiens SDL Slorth 0.928099 View
ENSG00000097007 ABL1 ENSG00000166797 FAM96A H. sapiens SDL Slorth 0.92808 View
ENSG00000097007 ABL1 ENSG00000175054 ATR H. sapiens SDL Slorth 0.928047 View
ENSG00000097007 ABL1 ENSG00000188419 CHM H. sapiens SDL Slorth 0.928042 View
ENSG00000097007 ABL1 ENSG00000171824 EXOSC10 H. sapiens SSL Slorth 0.928032 View
ENSG00000097007 ABL1 ENSG00000123975 CKS2 H. sapiens SDL Slorth 0.927935 View
ENSG00000097007 ABL1 ENSG00000163902 RPN1 H. sapiens SDL Slorth 0.927792 View
ENSG00000057663 ATG5 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.927653 View
ENSG00000097007 ABL1 ENSG00000177666 PNPLA2 H. sapiens SDL Slorth 0.927648 View
ENSG00000097007 ABL1 ENSG00000143322 ABL2 H. sapiens SSL Slorth 0.927605 View
ENSG00000097007 ABL1 ENSG00000148606 POLR3A H. sapiens SSL Slorth 0.927498 View
ENSG00000097007 ABL1 ENSG00000135521 LTV1 H. sapiens SSL Slorth 0.92749 View
ENSG00000097007 ABL1 ENSG00000196914 ARHGEF12 H. sapiens SSL Slorth 0.927476 View
ENSG00000097007 ABL1 ENSG00000101310 SEC23B H. sapiens SSL Slorth 0.927464 View
ENSG00000097007 ABL1 ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.92746 View
ENSG00000097007 ABL1 ENSG00000151239 TWF1 H. sapiens SDL Slorth 0.927439 View
ENSG00000097007 ABL1 ENSG00000184349 EFNA5 H. sapiens SDL Slorth 0.927409 View
ENSG00000097007 ABL1 ENSG00000170836 PPM1D H. sapiens SDL Slorth 0.927369 View
ENSG00000097007 ABL1 ENSG00000131467 PSME3 H. sapiens SDL Slorth 0.927331 View
ENSG00000097007 ABL1 ENSG00000172409 CLP1 H. sapiens SDL Slorth 0.927309 View
ENSG00000075624 ACTB ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.927304 View
ENSG00000097007 ABL1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.927265 View
ENSG00000097007 ABL1 ENSG00000122218 COPA H. sapiens SSL Slorth 0.927196 View
ENSG00000097007 ABL1 ENSG00000115866 DARS H. sapiens SSL Slorth 0.927194 View
ENSG00000097007 ABL1 ENSG00000147647 DPYS H. sapiens SDL Slorth 0.927174 View
ENSG00000097007 ABL1 ENSG00000144644 GADL1 H. sapiens SDL Slorth 0.927174 View
ENSG00000097007 ABL1 ENSG00000100297 MCM5 H. sapiens SDL Slorth 0.927153 View
ENSG00000097007 ABL1 ENSG00000184557 SOCS3 H. sapiens SSL Slorth 0.927109 View
ENSG00000063244 U2AF2 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.927058 View
ENSG00000097007 ABL1 ENSG00000135363 LMO2 H. sapiens SDL Slorth 0.927045 View
ENSG00000097007 ABL1 ENSG00000173674 EIF1AX H. sapiens SSL Slorth 0.927038 View
ENSG00000097007 ABL1 ENSG00000116016 EPAS1 H. sapiens SSL Slorth 0.927022 View
ENSG00000097007 ABL1 ENSG00000130382 MLLT1 H. sapiens SSL Slorth 0.926927 View
ENSG00000097007 ABL1 ENSG00000150907 FOXO1 H. sapiens SDL Slorth 0.926914 View
ENSG00000097007 ABL1 ENSG00000136574 GATA4 H. sapiens SDL Slorth 0.926865 View
ENSG00000097007 ABL1 ENSG00000188215 DCUN1D3 H. sapiens SDL Slorth 0.926853 View
ENSG00000097007 ABL1 ENSG00000113569 NUP155 H. sapiens SSL Slorth 0.926849 View
ENSG00000097007 ABL1 ENSG00000147065 MSN H. sapiens SSL Slorth 0.926826 View
ENSG00000097007 ABL1 ENSG00000172795 DCP2 H. sapiens SSL Slorth 0.926817 View
ENSG00000097007 ABL1 ENSG00000104388 RAB2A H. sapiens SSL Slorth 0.926801 View