ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000186868 MAPT H. sapiens SSL Slorth 0.93144 View
ENSG00000097007 ABL1 ENSG00000143756 FBXO28 H. sapiens SDL Slorth 0.931416 View
ENSG00000097007 ABL1 ENSG00000160949 TONSL H. sapiens SSL Slorth 0.931391 View
ENSG00000097007 ABL1 ENSG00000184787 UBE2G2 H. sapiens SDL Slorth 0.931387 View
ENSG00000097007 ABL1 ENSG00000140575 IQGAP1 H. sapiens SDL Slorth 0.931306 View
ENSG00000097007 ABL1 ENSG00000124214 STAU1 H. sapiens SDL Slorth 0.931277 View
ENSG00000097007 ABL1 ENSG00000136381 IREB2 H. sapiens SSL Slorth 0.931223 View
ENSG00000097007 ABL1 ENSG00000101442 ACTR5 H. sapiens SSL Slorth 0.931202 View
ENSG00000097007 ABL1 ENSG00000169398 PTK2 H. sapiens SDL Slorth 0.931118 View
ENSG00000097007 ABL1 ENSG00000100201 DDX17 H. sapiens SDL Slorth 0.93102 View
ENSG00000097007 ABL1 ENSG00000198612 COPS8 H. sapiens SSL Slorth 0.931007 View
ENSG00000097007 ABL1 ENSG00000188229 TUBB4B H. sapiens SSL Slorth 0.931003 View
ENSG00000086827 ZW10 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.930922 View
ENSG00000075624 ACTB ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.930902 View
ENSG00000097007 ABL1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.930875 View
ENSG00000097007 ABL1 ENSG00000178209 PLEC H. sapiens SSL Slorth 0.930872 View
ENSG00000080815 PSEN1 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.93083 View
ENSG00000097007 ABL1 ENSG00000115816 CEBPZ H. sapiens SDL Slorth 0.930801 View
ENSG00000092201 SUPT16H ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.930787 View
ENSG00000097007 ABL1 ENSG00000112742 TTK H. sapiens SDL Slorth 0.930727 View
ENSG00000097007 ABL1 ENSG00000198668 CALM1 H. sapiens SSL Slorth 0.930707 View
ENSG00000097007 ABL1 ENSG00000127463 EMC1 H. sapiens SDL Slorth 0.930639 View
ENSG00000097007 ABL1 ENSG00000133119 RFC3 H. sapiens SDL Slorth 0.930623 View
ENSG00000078140 UBE2K ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.930596 View
ENSG00000097007 ABL1 ENSG00000155363 MOV10 H. sapiens SSL Slorth 0.93056 View
ENSG00000097007 ABL1 ENSG00000113648 H2AFY H. sapiens SSL Slorth 0.930514 View
ENSG00000097007 ABL1 ENSG00000112237 CCNC H. sapiens SSL Slorth 0.93048 View
ENSG00000097007 ABL1 ENSG00000128731 HERC2 H. sapiens SDL Slorth 0.930457 View
ENSG00000097007 ABL1 ENSG00000100591 AHSA1 H. sapiens SSL Slorth 0.930382 View
ENSG00000097007 ABL1 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.930344 View
ENSG00000097007 ABL1 ENSG00000100650 SRSF5 H. sapiens SDL Slorth 0.930342 View
ENSG00000097007 ABL1 ENSG00000175104 TRAF6 H. sapiens SDL Slorth 0.930339 View
ENSG00000097007 ABL1 ENSG00000110321 EIF4G2 H. sapiens SSL Slorth 0.930331 View
ENSG00000097007 ABL1 ENSG00000102900 NUP93 H. sapiens SSL Slorth 0.930322 View
ENSG00000097007 ABL1 ENSG00000197879 MYO1C H. sapiens SSL Slorth 0.930275 View
ENSG00000097007 ABL1 ENSG00000164050 PLXNB1 H. sapiens SDL Slorth 0.930208 View
ENSG00000023445 BIRC3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.930177 View
ENSG00000097007 ABL1 ENSG00000146872 TLK2 H. sapiens SSL Slorth 0.930051 View
ENSG00000097007 ABL1 ENSG00000198911 SREBF2 H. sapiens SDL Slorth 0.930022 View
ENSG00000097007 ABL1 ENSG00000172315 TP53RK H. sapiens SSL Slorth 0.930021 View