ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000101966 XIAP H. sapiens SDL Slorth 0.934335 View
ENSG00000097007 ABL1 ENSG00000109819 PPARGC1A H. sapiens SSL Slorth 0.93428 View
ENSG00000097007 ABL1 ENSG00000106803 SEC61B H. sapiens SDL Slorth 0.934237 View
ENSG00000097007 ABL1 ENSG00000142731 PLK4 H. sapiens SSL Slorth 0.93417 View
ENSG00000097007 ABL1 ENSG00000122565 CBX3 H. sapiens SDL Slorth 0.934163 View
ENSG00000097007 ABL1 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.934096 View
ENSG00000097007 ABL1 ENSG00000119041 GTF3C3 H. sapiens SDL Slorth 0.93407 View
ENSG00000097007 ABL1 ENSG00000147162 OGT H. sapiens SDL Slorth 0.934061 View
ENSG00000097007 ABL1 ENSG00000273841 TAF9 H. sapiens SDL Slorth 0.933977 View
ENSG00000060237 WNK1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.933936 View
ENSG00000001626 CFTR ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.933915 View
ENSG00000097007 ABL1 ENSG00000102974 CTCF H. sapiens SSL Slorth 0.933752 View
ENSG00000097007 ABL1 ENSG00000131828 PDHA1 H. sapiens SDL Slorth 0.933677 View
ENSG00000097007 ABL1 ENSG00000160948 VPS28 H. sapiens SSL Slorth 0.933594 View
ENSG00000097007 ABL1 ENSG00000132254 ARFIP2 H. sapiens SSL Slorth 0.933594 View
ENSG00000097007 ABL1 ENSG00000186575 NF2 H. sapiens SDL Slorth 0.933533 View
ENSG00000097007 ABL1 ENSG00000160867 FGFR4 H. sapiens SSL Slorth 0.933466 View
ENSG00000097007 ABL1 ENSG00000101096 NFATC2 H. sapiens SSL Slorth 0.933456 View
ENSG00000097007 ABL1 ENSG00000136158 SPRY2 H. sapiens SSL Slorth 0.933368 View
ENSG00000055118 KCNH2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.933336 View
ENSG00000082805 ERC1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.933318 View
ENSG00000097007 ABL1 ENSG00000155959 VBP1 H. sapiens SSL Slorth 0.933257 View
ENSG00000097007 ABL1 ENSG00000269858 EGLN2 H. sapiens SSL Slorth 0.933198 View
ENSG00000097007 ABL1 ENSG00000131236 CAP1 H. sapiens SDL Slorth 0.933191 View
ENSG00000097007 ABL1 ENSG00000118058 KMT2A H. sapiens SDL Slorth 0.933155 View
ENSG00000097007 ABL1 ENSG00000166341 DCHS1 H. sapiens SDL Slorth 0.933154 View
ENSG00000097007 ABL1 ENSG00000186716 BCR H. sapiens SSL Slorth 0.933142 View
ENSG00000097007 ABL1 ENSG00000177733 HNRNPA0 H. sapiens SSL Slorth 0.933096 View
ENSG00000097007 ABL1 ENSG00000166501 PRKCB H. sapiens SDL Slorth 0.933069 View
ENSG00000097007 ABL1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.933054 View
ENSG00000097007 ABL1 ENSG00000103653 CSK H. sapiens SSL Slorth 0.933007 View
ENSG00000089159 PXN ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.932977 View
ENSG00000004897 CDC27 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.932874 View
ENSG00000097007 ABL1 ENSG00000103966 EHD4 H. sapiens SSL Slorth 0.932827 View
ENSG00000097007 ABL1 ENSG00000104964 AES H. sapiens SSL Slorth 0.932788 View
ENSG00000097007 ABL1 ENSG00000135473 PAN2 H. sapiens SSL Slorth 0.932777 View
ENSG00000097007 ABL1 ENSG00000113141 IK H. sapiens SDL Slorth 0.932773 View
ENSG00000097007 ABL1 ENSG00000165732 DDX21 H. sapiens SDL Slorth 0.932772 View
ENSG00000097007 ABL1 ENSG00000166900 STX3 H. sapiens SDL Slorth 0.932739 View
ENSG00000097007 ABL1 ENSG00000122126 OCRL H. sapiens SSL Slorth 0.932713 View