CFTR - ABL1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CFTR	ENSG00000001626	No diseases in record	CROFELEMER IVACAFTOR LUMACAFTOR	chloride channel activity intracellular ATPase-gated chloride channel activity protein binding ATP binding bicarbonate transmembrane transporter activity chloride transmembrane transporter activity chloride channel regulator activity chloride channel inhibitor activity enzyme binding PDZ domain binding ATPase-coupled anion transmembrane transporter activity	BPT1 (S. cerevisiae)
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)