ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000144749 LRIG1 H. sapiens SDL Slorth 0.9327 View
ENSG00000097007 ABL1 ENSG00000166974 MAPRE2 H. sapiens SSL Slorth 0.932699 View
ENSG00000097007 ABL1 ENSG00000137764 MAP2K5 H. sapiens SSL Slorth 0.932672 View
ENSG00000072062 PRKACA ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.932671 View
ENSG00000097007 ABL1 ENSG00000162298 SYVN1 H. sapiens SDL Slorth 0.932646 View
ENSG00000097007 ABL1 ENSG00000204435 CSNK2B H. sapiens SDL Slorth 0.932636 View
ENSG00000097007 ABL1 ENSG00000184304 PRKD1 H. sapiens SSL Slorth 0.932583 View
ENSG00000097007 ABL1 ENSG00000146731 CCT6A H. sapiens SDL Slorth 0.932578 View
ENSG00000097007 ABL1 ENSG00000155097 ATP6V1C1 H. sapiens SSL Slorth 0.932561 View
ENSG00000097007 ABL1 ENSG00000173402 DAG1 H. sapiens SSL Slorth 0.932462 View
ENSG00000097007 ABL1 ENSG00000173110 HSPA6 H. sapiens SDL Slorth 0.932372 View
ENSG00000097007 ABL1 ENSG00000122565 CBX3 H. sapiens SSL Slorth 0.932335 View
ENSG00000065361 ERBB3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.932305 View
ENSG00000010244 ZNF207 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.932242 View
ENSG00000097007 ABL1 ENSG00000166483 WEE1 H. sapiens SDL Slorth 0.932239 View
ENSG00000097007 ABL1 ENSG00000163029 SMC6 H. sapiens SSL Slorth 0.932228 View
ENSG00000094804 CDC6 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.932175 View
ENSG00000097007 ABL1 ENSG00000100813 ACIN1 H. sapiens SDL Slorth 0.932152 View
ENSG00000097007 ABL1 ENSG00000117713 ARID1A H. sapiens SSL Slorth 0.932112 View
ENSG00000097007 ABL1 ENSG00000163625 WDFY3 H. sapiens SSL Slorth 0.932081 View
ENSG00000097007 ABL1 ENSG00000114166 KAT2B H. sapiens SDL Slorth 0.93208 View
ENSG00000097007 ABL1 ENSG00000175643 RMI2 H. sapiens SSL Slorth 0.932067 View
ENSG00000097007 ABL1 ENSG00000118007 STAG1 H. sapiens SSL Slorth 0.931944 View
ENSG00000097007 ABL1 ENSG00000204388 HSPA1B H. sapiens SSL Slorth 0.931877 View
ENSG00000097007 ABL1 ENSG00000174243 DDX23 H. sapiens SSL Slorth 0.931839 View
ENSG00000097007 ABL1 ENSG00000117408 IPO13 H. sapiens SDL Slorth 0.931767 View
ENSG00000097007 ABL1 ENSG00000204209 DAXX H. sapiens SDL Slorth 0.931765 View
ENSG00000097007 ABL1 ENSG00000173757 STAT5B H. sapiens SDL Slorth 0.931764 View
ENSG00000097007 ABL1 ENSG00000117676 RPS6KA1 H. sapiens SDL Slorth 0.93176 View
ENSG00000097007 ABL1 ENSG00000122367 LDB3 H. sapiens SDL Slorth 0.931703 View
ENSG00000097007 ABL1 ENSG00000161202 DVL3 H. sapiens SSL Slorth 0.931687 View
ENSG00000097007 ABL1 ENSG00000180353 HCLS1 H. sapiens SSL Slorth 0.931682 View
ENSG00000097007 ABL1 ENSG00000173207 CKS1B H. sapiens SDL Slorth 0.931655 View
ENSG00000097007 ABL1 ENSG00000120837 NFYB H. sapiens SSL Slorth 0.931642 View
ENSG00000097007 ABL1 ENSG00000103275 UBE2I H. sapiens SDL Slorth 0.93164 View
ENSG00000097007 ABL1 ENSG00000101146 RAE1 H. sapiens SSL Slorth 0.931621 View
ENSG00000097007 ABL1 ENSG00000171497 PPID H. sapiens SSL Slorth 0.931606 View
ENSG00000097007 ABL1 ENSG00000163930 BAP1 H. sapiens SSL Slorth 0.931492 View
ENSG00000097007 ABL1 ENSG00000136152 COG3 H. sapiens SSL Slorth 0.931479 View
ENSG00000097007 ABL1 ENSG00000242247 ARFGAP3 H. sapiens SSL Slorth 0.931451 View