Go term | Description |
---|---|
GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity |
GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity |
GO:0005515 | protein binding |
GO:0008144 | drug binding |
GO:0019899 | enzyme binding |
GO:0030552 | cAMP binding |
GO:0031698 | beta-2 adrenergic receptor binding |
GO:0044325 | ion channel binding |
GO:0046872 | metal ion binding |
GO:0051117 | ATPase binding |
GO:0097110 | scaffold protein binding |
Drug name | Description |
---|---|
AMLEXANOX | Phosphodiesterase 4 inhibitor |
APREMILAST | Phosphodiesterase 4 inhibitor |
DIPYRIDAMOLE | |
DYPHYLLINE | Phosphodiesterase 4 inhibitor |
FLAVOXATE | Phosphodiesterase 4 inhibitor |
PENTOXIFYLLINE | Adenosine A2 receptor antagonist |
ROFLUMILAST | Phosphodiesterase 4 inhibitor |
THEOPHYLLINE | Adenosine receptor antagonist |
THEOPHYLLINE GLYCINATE | Adenosine receptor antagonist |
No diseases in record
Gene | Organism | |
---|---|---|
pde-4 | C. elegans | |
dnc | D. melanogaster |
Gene ID A | Gene Name A | Gene ID B | Gene Symbol B | Organism | Source | Score? | ||
---|---|---|---|---|---|---|---|---|
ENSG00000100030 | MAPK1 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.987273 | View |
ENSG00000113448 | PDE4D | ENSG00000170315 | UBB | H. sapiens | SDL | Slorth | 0.982463 | View |
ENSG00000101266 | CSNK2A1 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.980899 | View |
ENSG00000109670 | FBXW7 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.977516 | View |
ENSG00000055130 | CUL1 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.97733 | View |
ENSG00000113448 | PDE4D | ENSG00000150991 | UBC | H. sapiens | SDL | Slorth | 0.974351 | View |
ENSG00000113448 | PDE4D | ENSG00000141510 | TP53 | H. sapiens | SDL | Slorth | 0.973736 | View |
ENSG00000104365 | IKBKB | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.97288 | View |
ENSG00000110395 | CBL | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.97206 | View |
ENSG00000113448 | PDE4D | ENSG00000177885 | GRB2 | H. sapiens | SDL | Slorth | 0.968492 | View |
ENSG00000113448 | PDE4D | ENSG00000133703 | KRAS | H. sapiens | SSL | Slorth | 0.968141 | View |
ENSG00000100393 | EP300 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.967293 | View |
ENSG00000113448 | PDE4D | ENSG00000173039 | RELA | H. sapiens | SDL | Slorth | 0.966814 | View |
ENSG00000113448 | PDE4D | ENSG00000132646 | PCNA | H. sapiens | SDL | Slorth | 0.966445 | View |
ENSG00000113448 | PDE4D | ENSG00000177606 | JUN | H. sapiens | SDL | Slorth | 0.966348 | View |
ENSG00000113448 | PDE4D | ENSG00000197122 | SRC | H. sapiens | SDL | Slorth | 0.965449 | View |
ENSG00000113448 | PDE4D | ENSG00000142208 | AKT1 | H. sapiens | SDL | Slorth | 0.964524 | View |
ENSG00000113448 | PDE4D | ENSG00000136997 | MYC | H. sapiens | SDL | Slorth | 0.96441 | View |
ENSG00000005339 | CREBBP | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.96434 | View |
ENSG00000113448 | PDE4D | ENSG00000166167 | BTRC | H. sapiens | SDL | Slorth | 0.962503 | View |
ENSG00000080824 | HSP90AA1 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.962357 | View |
ENSG00000113448 | PDE4D | ENSG00000162385 | MAGOH | H. sapiens | SDL | Slorth | 0.961828 | View |
ENSG00000097007 | ABL1 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.960053 | View |
ENSG00000113448 | PDE4D | ENSG00000146648 | EGFR | H. sapiens | SDL | Slorth | 0.959838 | View |
ENSG00000113448 | PDE4D | ENSG00000175104 | TRAF6 | H. sapiens | SDL | Slorth | 0.959753 | View |
ENSG00000101146 | RAE1 | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.959365 | View |
ENSG00000082701 | GSK3B | ENSG00000113448 | PDE4D | H. sapiens | SSL | Slorth | 0.95907 | View |
ENSG00000113448 | PDE4D | ENSG00000166949 | SMAD3 | H. sapiens | SDL | Slorth | 0.958485 | View |
ENSG00000113448 | PDE4D | ENSG00000116478 | HDAC1 | H. sapiens | SDL | Slorth | 0.958001 | View |
ENSG00000096384 | HSP90AB1 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.957339 | View |
ENSG00000113448 | PDE4D | ENSG00000169083 | AR | H. sapiens | SDL | Slorth | 0.95606 | View |
ENSG00000113448 | PDE4D | ENSG00000123374 | CDK2 | H. sapiens | SDL | Slorth | 0.955994 | View |
ENSG00000100906 | NFKBIA | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.955474 | View |
ENSG00000109320 | NFKB1 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.953287 | View |
ENSG00000012048 | BRCA1 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.952169 | View |
ENSG00000113448 | PDE4D | ENSG00000168036 | CTNNB1 | H. sapiens | SDL | Slorth | 0.951203 | View |
ENSG00000091831 | ESR1 | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.948304 | View |
ENSG00000113448 | PDE4D | ENSG00000188612 | SUMO2 | H. sapiens | SDL | Slorth | 0.947569 | View |
ENSG00000113448 | PDE4D | ENSG00000124762 | CDKN1A | H. sapiens | SDL | Slorth | 0.947196 | View |
ENSG00000103275 | UBE2I | ENSG00000113448 | PDE4D | H. sapiens | SDL | Slorth | 0.946615 | View |