PDE4D

ENSG00000113448 - H. sapiens

Pathways

Go term Description
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005515 protein binding
GO:0008144 drug binding
GO:0019899 enzyme binding
GO:0030552 cAMP binding
GO:0031698 beta-2 adrenergic receptor binding
GO:0044325 ion channel binding
GO:0046872 metal ion binding
GO:0051117 ATPase binding
GO:0097110 scaffold protein binding

Drugs

Drug name Description
AMLEXANOX Phosphodiesterase 4 inhibitor
APREMILAST Phosphodiesterase 4 inhibitor
DIPYRIDAMOLE
DYPHYLLINE Phosphodiesterase 4 inhibitor
FLAVOXATE Phosphodiesterase 4 inhibitor
PENTOXIFYLLINE Adenosine A2 receptor antagonist
ROFLUMILAST Phosphodiesterase 4 inhibitor
THEOPHYLLINE Adenosine receptor antagonist
THEOPHYLLINE GLYCINATE Adenosine receptor antagonist

Diseases

No diseases in record

Orthologs

Gene Organism
pde-4 C. elegans
dnc D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000100030 MAPK1 ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.987273 View
ENSG00000113448 PDE4D ENSG00000170315 UBB H. sapiens SDL Slorth 0.982463 View
ENSG00000101266 CSNK2A1 ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.980899 View
ENSG00000109670 FBXW7 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.977516 View
ENSG00000055130 CUL1 ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.97733 View
ENSG00000113448 PDE4D ENSG00000150991 UBC H. sapiens SDL Slorth 0.974351 View
ENSG00000113448 PDE4D ENSG00000141510 TP53 H. sapiens SDL Slorth 0.973736 View
ENSG00000104365 IKBKB ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.97288 View
ENSG00000110395 CBL ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.97206 View
ENSG00000113448 PDE4D ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.968492 View
ENSG00000113448 PDE4D ENSG00000133703 KRAS H. sapiens SSL Slorth 0.968141 View
ENSG00000100393 EP300 ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.967293 View
ENSG00000113448 PDE4D ENSG00000173039 RELA H. sapiens SDL Slorth 0.966814 View
ENSG00000113448 PDE4D ENSG00000132646 PCNA H. sapiens SDL Slorth 0.966445 View
ENSG00000113448 PDE4D ENSG00000177606 JUN H. sapiens SDL Slorth 0.966348 View
ENSG00000113448 PDE4D ENSG00000197122 SRC H. sapiens SDL Slorth 0.965449 View
ENSG00000113448 PDE4D ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.964524 View
ENSG00000113448 PDE4D ENSG00000136997 MYC H. sapiens SDL Slorth 0.96441 View
ENSG00000005339 CREBBP ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.96434 View
ENSG00000113448 PDE4D ENSG00000166167 BTRC H. sapiens SDL Slorth 0.962503 View
ENSG00000080824 HSP90AA1 ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.962357 View
ENSG00000113448 PDE4D ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.961828 View
ENSG00000097007 ABL1 ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.960053 View
ENSG00000113448 PDE4D ENSG00000146648 EGFR H. sapiens SDL Slorth 0.959838 View
ENSG00000113448 PDE4D ENSG00000175104 TRAF6 H. sapiens SDL Slorth 0.959753 View
ENSG00000101146 RAE1 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.959365 View
ENSG00000082701 GSK3B ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.95907 View
ENSG00000113448 PDE4D ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.958485 View
ENSG00000113448 PDE4D ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.958001 View
ENSG00000096384 HSP90AB1 ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.957339 View
ENSG00000113448 PDE4D ENSG00000169083 AR H. sapiens SDL Slorth 0.95606 View
ENSG00000113448 PDE4D ENSG00000123374 CDK2 H. sapiens SDL Slorth 0.955994 View
ENSG00000100906 NFKBIA ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.955474 View
ENSG00000109320 NFKB1 ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.953287 View
ENSG00000012048 BRCA1 ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.952169 View
ENSG00000113448 PDE4D ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.951203 View
ENSG00000091831 ESR1 ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.948304 View
ENSG00000113448 PDE4D ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.947569 View
ENSG00000113448 PDE4D ENSG00000124762 CDKN1A H. sapiens SDL Slorth 0.947196 View
ENSG00000103275 UBE2I ENSG00000113448 PDE4D H. sapiens SDL Slorth 0.946615 View