PDE4D

ENSG00000113448 - H. sapiens

Pathways

Go term Description
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005515 protein binding
GO:0008144 drug binding
GO:0019899 enzyme binding
GO:0030552 cAMP binding
GO:0031698 beta-2 adrenergic receptor binding
GO:0044325 ion channel binding
GO:0046872 metal ion binding
GO:0051117 ATPase binding
GO:0097110 scaffold protein binding

Drugs

Drug name Description
AMLEXANOX Phosphodiesterase 4 inhibitor
APREMILAST Phosphodiesterase 4 inhibitor
DIPYRIDAMOLE
DYPHYLLINE Phosphodiesterase 4 inhibitor
FLAVOXATE Phosphodiesterase 4 inhibitor
PENTOXIFYLLINE Adenosine A2 receptor antagonist
ROFLUMILAST Phosphodiesterase 4 inhibitor
THEOPHYLLINE Adenosine receptor antagonist
THEOPHYLLINE GLYCINATE Adenosine receptor antagonist

Diseases

No diseases in record

Orthologs

Gene Organism
pde-4 C. elegans
dnc D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000078140 UBE2K ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.879886 View
ENSG00000070010 UFD1L ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.87842 View
ENSG00000096384 HSP90AB1 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.872351 View
ENSG00000110092 CCND1 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.869491 View
ENSG00000005339 CREBBP ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.866076 View
ENSG00000004897 CDC27 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.856358 View
ENSG00000075624 ACTB ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.856161 View
ENSG00000100906 NFKBIA ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.84894 View
ENSG00000109971 HSPA8 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.84543 View
ENSG00000036257 CUL3 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.84157 View
ENSG00000049759 NEDD4L ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.838858 View
ENSG00000067560 RHOA ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.837125 View
ENSG00000111276 CDKN1B ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.83437 View
ENSG00000080815 PSEN1 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.833258 View
ENSG00000112592 TBP ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.832574 View
ENSG00000109320 NFKB1 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.832175 View
ENSG00000058729 RIOK2 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.82902 View
ENSG00000070831 CDC42 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.827018 View
ENSG00000100644 HIF1A ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.825811 View
ENSG00000091831 ESR1 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.822872 View
ENSG00000100028 SNRPD3 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.8104 View
ENSG00000094804 CDC6 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.807095 View
ENSG00000101966 XIAP ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.80507 View
ENSG00000280548 FBL ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.795697 View
ENSG00000093009 CDC45 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.790928 View
ENSG00000073111 MCM2 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.78348 View
ENSG00000112118 MCM3 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.782913 View
ENSG00000108424 KPNB1 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.781981 View
ENSG00000006451 RALA ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.780842 View
ENSG00000069869 NEDD4 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.779624 View
ENSG00000113448 PDE4D ENSG00000118503 TNFAIP3 H. sapiens SSL Slorth 0.773045 View
ENSG00000096968 JAK2 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.768879 View
ENSG00000113448 PDE4D ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.768758 View
ENSG00000113448 PDE4D ENSG00000283094 PTEN H. sapiens SSL Slorth 0.76688 View
ENSG00000072518 MARK2 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.766201 View
ENSG00000084774 CAD ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.764083 View
ENSG00000072803 FBXW11 ENSG00000113448 PDE4D H. sapiens SSL Slorth 0.76057 View
ENSG00000113448 PDE4D ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.752675 View