FGFR1

ENSG00000077782 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008201 heparin binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0017134 fibroblast growth factor binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
MPN
NHL
salivary adenoma

Orthologs

Gene Organism
egl-15 C. elegans
htl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077782 FGFR1 ENSG00000080824 HSP90AA1 H. sapiens SDL Slorth 0.900025 View
ENSG00000077782 FGFR1 ENSG00000096968 JAK2 H. sapiens SSL Slorth 0.899614 View
ENSG00000077782 FGFR1 ENSG00000254087 LYN H. sapiens SSL Slorth 0.899411 View
ENSG00000077782 FGFR1 ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.898974 View
ENSG00000077782 FGFR1 ENSG00000140464 PML H. sapiens SSL Slorth 0.898579 View
ENSG00000055332 EIF2AK2 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.898226 View
ENSG00000077782 FGFR1 ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.898005 View
ENSG00000077782 FGFR1 ENSG00000165416 SUGT1 H. sapiens SSL Slorth 0.897582 View
ENSG00000077782 FGFR1 ENSG00000130726 TRIM28 H. sapiens SSL Slorth 0.897307 View
ENSG00000077782 FGFR1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.897296 View
ENSG00000077782 FGFR1 ENSG00000157404 KIT H. sapiens SSL Slorth 0.897155 View
ENSG00000077782 FGFR1 ENSG00000145386 CCNA2 H. sapiens SSL Slorth 0.89696 View
ENSG00000077782 FGFR1 ENSG00000166851 PLK1 H. sapiens SSL Slorth 0.896883 View
ENSG00000077782 FGFR1 ENSG00000104365 IKBKB H. sapiens SSL Slorth 0.896359 View
ENSG00000077782 FGFR1 ENSG00000134982 APC H. sapiens SSL Slorth 0.896298 View
ENSG00000077782 FGFR1 ENSG00000144028 SNRNP200 H. sapiens SSL Slorth 0.895999 View
ENSG00000077782 FGFR1 ENSG00000114166 KAT2B H. sapiens SSL Slorth 0.895724 View
ENSG00000077782 FGFR1 ENSG00000108953 YWHAE H. sapiens SSL Slorth 0.895701 View
ENSG00000077782 FGFR1 ENSG00000124762 CDKN1A H. sapiens SSL Slorth 0.894326 View
ENSG00000077782 FGFR1 ENSG00000136450 SRSF1 H. sapiens SSL Slorth 0.894278 View
ENSG00000077782 FGFR1 ENSG00000102882 MAPK3 H. sapiens SSL Slorth 0.894247 View
ENSG00000077782 FGFR1 ENSG00000106799 TGFBR1 H. sapiens SSL Slorth 0.894176 View
ENSG00000077782 FGFR1 ENSG00000128052 KDR H. sapiens SSL Slorth 0.894136 View
ENSG00000077782 FGFR1 ENSG00000114503 NCBP2 H. sapiens SSL Slorth 0.893632 View
ENSG00000077782 FGFR1 ENSG00000119048 UBE2B H. sapiens SSL Slorth 0.893313 View
ENSG00000077782 FGFR1 ENSG00000099817 POLR2E H. sapiens SSL Slorth 0.893062 View
ENSG00000077782 FGFR1 ENSG00000197299 BLM H. sapiens SSL Slorth 0.892901 View
ENSG00000077782 FGFR1 ENSG00000105173 CCNE1 H. sapiens SSL Slorth 0.89269 View
ENSG00000077782 FGFR1 ENSG00000105974 CAV1 H. sapiens SSL Slorth 0.892092 View
ENSG00000077782 FGFR1 ENSG00000105568 PPP2R1A H. sapiens SSL Slorth 0.89192 View
ENSG00000077782 FGFR1 ENSG00000115904 SOS1 H. sapiens SSL Slorth 0.891802 View
ENSG00000077782 FGFR1 ENSG00000132383 RPA1 H. sapiens SSL Slorth 0.891753 View
ENSG00000077782 FGFR1 ENSG00000156970 BUB1B H. sapiens SSL Slorth 0.891501 View
ENSG00000077782 FGFR1 ENSG00000105401 CDC37 H. sapiens SSL Slorth 0.891267 View
ENSG00000077782 FGFR1 ENSG00000096384 HSP90AB1 H. sapiens SSL Slorth 0.890723 View
ENSG00000077782 FGFR1 ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.890425 View
ENSG00000077782 FGFR1 ENSG00000159216 RUNX1 H. sapiens SSL Slorth 0.889894 View
ENSG00000077782 FGFR1 ENSG00000087586 AURKA H. sapiens SSL Slorth 0.889492 View
ENSG00000077782 FGFR1 ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.889353 View
ENSG00000077782 FGFR1 ENSG00000169398 PTK2 H. sapiens SSL Slorth 0.889085 View