FGFR1

ENSG00000077782 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008201 heparin binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0017134 fibroblast growth factor binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
MPN
NHL
salivary adenoma

Orthologs

Gene Organism
egl-15 C. elegans
htl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077782 FGFR1 ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.877234 View
ENSG00000077782 FGFR1 ENSG00000100297 MCM5 H. sapiens SSL Slorth 0.876784 View
ENSG00000077782 FGFR1 ENSG00000110330 BIRC2 H. sapiens SSL Slorth 0.876263 View
ENSG00000077782 FGFR1 ENSG00000196591 HDAC2 H. sapiens SSL Slorth 0.876237 View
ENSG00000077782 FGFR1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.876128 View
ENSG00000077782 FGFR1 ENSG00000171791 BCL2 H. sapiens SSL Slorth 0.875896 View
ENSG00000077782 FGFR1 ENSG00000170312 CDK1 H. sapiens SSL Slorth 0.875229 View
ENSG00000077782 FGFR1 ENSG00000163932 PRKCD H. sapiens SSL Slorth 0.874844 View
ENSG00000077782 FGFR1 ENSG00000169750 RAC3 H. sapiens SSL Slorth 0.874756 View
ENSG00000077782 FGFR1 ENSG00000105325 FZR1 H. sapiens SSL Slorth 0.87464 View
ENSG00000077782 FGFR1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.874617 View
ENSG00000066468 FGFR2 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.874006 View
ENSG00000072401 UBE2D1 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.873851 View
ENSG00000077782 FGFR1 ENSG00000134308 YWHAQ H. sapiens SSL Slorth 0.872993 View
ENSG00000077782 FGFR1 ENSG00000124181 PLCG1 H. sapiens SSL Slorth 0.872981 View
ENSG00000077782 FGFR1 ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.872792 View
ENSG00000077782 FGFR1 ENSG00000170606 HSPA4 H. sapiens SSL Slorth 0.872722 View
ENSG00000077782 FGFR1 ENSG00000126457 PRMT1 H. sapiens SSL Slorth 0.872301 View
ENSG00000077782 FGFR1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.87226 View
ENSG00000077782 FGFR1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.872083 View
ENSG00000067606 PRKCZ ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.872064 View
ENSG00000075089 ACTR6 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.871867 View
ENSG00000077782 FGFR1 ENSG00000177606 JUN H. sapiens SSL Slorth 0.871616 View
ENSG00000077782 FGFR1 ENSG00000082701 GSK3B H. sapiens SSL Slorth 0.871199 View
ENSG00000077782 FGFR1 ENSG00000108094 CUL2 H. sapiens SSL Slorth 0.870991 View
ENSG00000077782 FGFR1 ENSG00000106462 EZH2 H. sapiens SSL Slorth 0.870985 View
ENSG00000077782 FGFR1 ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.870753 View
ENSG00000077782 FGFR1 ENSG00000110107 PRPF19 H. sapiens SSL Slorth 0.870285 View
ENSG00000077782 FGFR1 ENSG00000115524 SF3B1 H. sapiens SSL Slorth 0.869828 View
ENSG00000077782 FGFR1 ENSG00000135018 UBQLN1 H. sapiens SSL Slorth 0.869822 View
ENSG00000055130 CUL1 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.869236 View
ENSG00000070950 RAD18 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.869149 View
ENSG00000077782 FGFR1 ENSG00000159692 CTBP1 H. sapiens SSL Slorth 0.868977 View
ENSG00000077782 FGFR1 ENSG00000185359 HGS H. sapiens SSL Slorth 0.868686 View
ENSG00000053900 ANAPC4 ENSG00000077782 FGFR1 H. sapiens SSL Slorth 0.868554 View
ENSG00000077782 FGFR1 ENSG00000132341 RAN H. sapiens SSL Slorth 0.868107 View
ENSG00000077782 FGFR1 ENSG00000103194 USP10 H. sapiens SSL Slorth 0.867049 View
ENSG00000077782 FGFR1 ENSG00000095015 MAP3K1 H. sapiens SSL Slorth 0.865688 View
ENSG00000077782 FGFR1 ENSG00000100138 SNU13 H. sapiens SSL Slorth 0.864972 View
ENSG00000077782 FGFR1 ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.864748 View