FGFR1 - TGFBR1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FGFR1	ENSG00000077782	MPN NHL salivary adenoma	LENVATINIB NINTEDANIB PAZOPANIB PONATINIB REGORAFENIB	protein tyrosine kinase activity fibroblast growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding heparin binding 1-phosphatidylinositol-3-kinase activity fibroblast growth factor binding identical protein binding protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity	egl-15 (C. elegans) htl (D. melanogaster)
TGFBR1	ENSG00000106799	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity transforming growth factor beta-activated receptor activity transforming growth factor beta receptor activity, type I signal transducer activity, downstream of receptor type II transforming growth factor beta receptor binding protein binding ATP binding SMAD binding metal ion binding transforming growth factor beta binding I-SMAD binding growth factor binding	babo (D. melanogaster)