MAP2K2

ENSG00000126934 - H. sapiens

Pathways

Go term Description
GO:0004674 protein serine/threonine kinase activity
GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity
GO:0004708 MAP kinase kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0030165 PDZ domain binding
GO:0043539 protein serine/threonine kinase activator activity
GO:0046872 metal ion binding
GO:0097110 scaffold protein binding

Drugs

Drug name Description
TRAMETINIB Dual specificity mitogen-activated protein kinase kinase 2 inhibitor

Diseases

Disease Name
NSCLC
melanoma

Orthologs

Gene Organism
PBS2 S. cerevisiae
mek-2 C. elegans
Dsor1 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000070756 PABPC1 ENSG00000126934 MAP2K2 H. sapiens SSL Slorth 0.764249 View
ENSG00000089159 PXN ENSG00000126934 MAP2K2 H. sapiens SSL Slorth 0.763534 View
ENSG00000074319 TSG101 ENSG00000126934 MAP2K2 H. sapiens SSL Slorth 0.763169 View
ENSG00000114867 EIF4G1 ENSG00000126934 MAP2K2 H. sapiens SSL Slorth 0.761835 View
ENSG00000126934 MAP2K2 ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.760927 View
ENSG00000126934 MAP2K2 ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.760855 View
ENSG00000070950 RAD18 ENSG00000126934 MAP2K2 H. sapiens SSL Slorth 0.759062 View
ENSG00000124486 USP9X ENSG00000126934 MAP2K2 H. sapiens SSL Slorth 0.758408 View
ENSG00000126934 MAP2K2 ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.756253 View
ENSG00000107581 EIF3A ENSG00000126934 MAP2K2 H. sapiens SSL Slorth 0.753193 View
ENSG00000126934 MAP2K2 ENSG00000135486 HNRNPA1 H. sapiens SSL Slorth 0.751152 View