EIF4G1 - MAP2K2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EIF4G1	ENSG00000114867	No diseases in record	No drugs in record	translation initiation factor activity protein binding translation factor activity, RNA binding eukaryotic initiation factor 4E binding cadherin binding involved in cell-cell adhesion	TIF4631 (S. cerevisiae) TIF4632 (S. cerevisiae) ifg-1 (C. elegans) eIF4G2 (D. melanogaster)
MAP2K2	ENSG00000126934	NSCLC melanoma	TRAMETINIB	protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding PDZ domain binding protein serine/threonine kinase activator activity metal ion binding scaffold protein binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)