RAD18 - MAP2K2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAD18	ENSG00000070950	No diseases in record	No drugs in record	Y-form DNA binding damaged DNA binding protein binding zinc ion binding ligase activity polyubiquitin binding ubiquitin protein ligase binding protein complex binding identical protein binding single-stranded DNA-dependent ATPase activity ubiquitin protein ligase activity single-stranded DNA binding transferase activity DNA binding metal ion binding	RAD18 (S. cerevisiae)
MAP2K2	ENSG00000126934	NSCLC melanoma	TRAMETINIB	protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding PDZ domain binding protein serine/threonine kinase activator activity metal ion binding scaffold protein binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)