IDH1

ENSG00000138413 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0004450 isocitrate dehydrogenase (NADP+) activity
GO:0005102 receptor binding
GO:0042803 protein homodimerization activity
GO:0050661 NADP binding
GO:0051287 NAD binding
GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity
GO:0098641 cadherin binding involved in cell-cell adhesion
GO:0004449 isocitrate dehydrogenase (NAD+) activity
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0003723 RNA binding
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0046872 metal ion binding

Drugs

No drugs in record

Diseases

Disease Name
glioblastoma

Orthologs

Gene Organism
IDP1 S. cerevisiae
IDP2 S. cerevisiae
IDP3 S. cerevisiae

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000109670 FBXW7 ENSG00000138413 IDH1 H. sapiens SSL Slorth 0.980875 View
ENSG00000133703 KRAS ENSG00000138413 IDH1 H. sapiens SSL Slorth 0.978251 View
ENSG00000110395 CBL ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.97352 View
ENSG00000080824 HSP90AA1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.969392 View
ENSG00000138413 IDH1 ENSG00000177606 JUN H. sapiens SDL Slorth 0.968545 View
ENSG00000136997 MYC ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.966823 View
ENSG00000101266 CSNK2A1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.966187 View
ENSG00000096384 HSP90AB1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.965866 View
ENSG00000109971 HSPA8 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.965521 View
ENSG00000005339 CREBBP ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.965478 View
ENSG00000012048 BRCA1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.965472 View
ENSG00000123374 CDK2 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.965324 View
ENSG00000103275 UBE2I ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.965228 View
ENSG00000132646 PCNA ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.965187 View
ENSG00000100393 EP300 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.965085 View
ENSG00000091831 ESR1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.964675 View
ENSG00000116478 HDAC1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.96393 View
ENSG00000138413 IDH1 ENSG00000185591 SP1 H. sapiens SDL Slorth 0.963852 View
ENSG00000132155 RAF1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.963689 View
ENSG00000100644 HIF1A ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.96322 View
ENSG00000138413 IDH1 ENSG00000140464 PML H. sapiens SDL Slorth 0.96257 View
ENSG00000138413 IDH1 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.961912 View
ENSG00000138413 IDH1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.961584 View
ENSG00000097007 ABL1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.961377 View
ENSG00000138413 IDH1 ENSG00000169083 AR H. sapiens SDL Slorth 0.961243 View
ENSG00000113558 SKP1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.960619 View
ENSG00000121022 COPS5 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.960486 View
ENSG00000138413 IDH1 ENSG00000173039 RELA H. sapiens SDL Slorth 0.959991 View
ENSG00000104365 IKBKB ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.959652 View
ENSG00000138413 IDH1 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.959075 View
ENSG00000101146 RAE1 ENSG00000138413 IDH1 H. sapiens SSL Slorth 0.958749 View
ENSG00000138413 IDH1 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.95846 View
ENSG00000109320 NFKB1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.95767 View
ENSG00000138413 IDH1 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.956682 View
ENSG00000110092 CCND1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.956471 View
ENSG00000138413 IDH1 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.956225 View
ENSG00000100030 MAPK1 ENSG00000138413 IDH1 H. sapiens SDL Slorth 0.956108 View
ENSG00000138413 IDH1 ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.95584 View
ENSG00000138413 IDH1 ENSG00000150991 UBC H. sapiens SDL Slorth 0.955612 View
ENSG00000138413 IDH1 ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.95532 View