HDAC1 - IDH1

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC1	ENSG00000116478	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	transcription regulatory region sequence-specific DNA binding core promoter binding RNA polymerase II transcription factor binding RNA polymerase II repressing transcription factor binding RNA polymerase II transcription corepressor activity transcription factor activity, sequence-specific DNA binding histone deacetylase activity protein binding transcription factor binding deacetylase activity enzyme binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity activating transcription factor binding histone deacetylase binding transcription regulatory region DNA binding protein N-terminus binding NF-kappaB binding repressing transcription factor binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	RPD3 (S. cerevisiae) hda-1 (C. elegans) hda-3 (C. elegans)
IDH1	ENSG00000138413	glioblastoma	No drugs in record	magnesium ion binding isocitrate dehydrogenase (NADP+) activity receptor binding protein homodimerization activity NADP binding NAD binding (R)-2-hydroxyglutarate dehydrogenase activity cadherin binding involved in cell-cell adhesion isocitrate dehydrogenase (NAD+) activity catalytic activity oxidoreductase activity RNA binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor metal ion binding	IDP1 (S. cerevisiae) IDP2 (S. cerevisiae) IDP3 (S. cerevisiae)