IDH1 - JUN

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IDH1	ENSG00000138413	glioblastoma	No drugs in record	magnesium ion binding isocitrate dehydrogenase (NADP+) activity receptor binding protein homodimerization activity NADP binding NAD binding (R)-2-hydroxyglutarate dehydrogenase activity cadherin binding involved in cell-cell adhesion isocitrate dehydrogenase (NAD+) activity catalytic activity oxidoreductase activity RNA binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor metal ion binding	IDP1 (S. cerevisiae) IDP2 (S. cerevisiae) IDP3 (S. cerevisiae)
JUN	ENSG00000177606	sarcoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II activating transcription factor binding transcriptional activator activity, RNA polymerase II transcription factor binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding transcription coactivator activity GTPase activator activity protein binding transcription factor binding enzyme binding cAMP response element binding identical protein binding protein homodimerization activity transcription regulatory region DNA binding protein heterodimerization activity R-SMAD binding HMG box domain binding	Jra (D. melanogaster)