IDH1 - HDAC2

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
IDH1 ENSG00000138413 glioblastoma

No drugs in record

magnesium ion binding
isocitrate dehydrogenase (NADP+) activity
receptor binding
protein homodimerization activity
NADP binding
NAD binding
(R)-2-hydroxyglutarate dehydrogenase activity
cadherin binding involved in cell-cell adhesion
isocitrate dehydrogenase (NAD+) activity
catalytic activity
oxidoreductase activity
RNA binding
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
metal ion binding
IDP1 (S. cerevisiae)
IDP2 (S. cerevisiae)
IDP3 (S. cerevisiae)
HDAC2 ENSG00000196591

No diseases in record

BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
VORINOSTAT
core promoter binding
RNA polymerase II repressing transcription factor binding
chromatin binding
histone deacetylase activity
protein binding
transcription factor binding
deacetylase activity
enzyme binding
heat shock protein binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
sequence-specific DNA binding
NF-kappaB binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
nucleosomal DNA binding
RPD3 (S. cerevisiae)
hda-1 (C. elegans)
hda-3 (C. elegans)