IDH1 - HDAC2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IDH1	ENSG00000138413	glioblastoma	No drugs in record	magnesium ion binding isocitrate dehydrogenase (NADP+) activity receptor binding protein homodimerization activity NADP binding NAD binding (R)-2-hydroxyglutarate dehydrogenase activity cadherin binding involved in cell-cell adhesion isocitrate dehydrogenase (NAD+) activity catalytic activity oxidoreductase activity RNA binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor metal ion binding	IDP1 (S. cerevisiae) IDP2 (S. cerevisiae) IDP3 (S. cerevisiae)
HDAC2	ENSG00000196591	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	core promoter binding RNA polymerase II repressing transcription factor binding chromatin binding histone deacetylase activity protein binding transcription factor binding deacetylase activity enzyme binding heat shock protein binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity sequence-specific DNA binding NF-kappaB binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	RPD3 (S. cerevisiae) hda-1 (C. elegans) hda-3 (C. elegans)