DOT1L

ENSG00000104885 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0018024 histone-lysine N-methyltransferase activity
GO:0031151 histone methyltransferase activity (H3-K79 specific)
GO:0042054 histone methyltransferase activity

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
DOT1 S. cerevisiae
gpp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000171552 BCL2L1 ENSG00000104885 DOT1L H. sapiens SSL BioGRID 1.0 View
ENSG00000142453 CARM1 ENSG00000104885 DOT1L H. sapiens SSL BioGRID 1.0 View
ENSG00000104885 DOT1L ENSG00000143384 MCL1 H. sapiens SSL BioGRID 1.0 View
ENSG00000104885 DOT1L ENSG00000164078 MST1R H. sapiens SSL BioGRID 1.0 View
ENSG00000101266 CSNK2A1 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.988565 View
ENSG00000005339 CREBBP ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.986221 View
ENSG00000091831 ESR1 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.985555 View
ENSG00000012048 BRCA1 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.984085 View
ENSG00000104885 DOT1L ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.978962 View
ENSG00000100393 EP300 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.977544 View
ENSG00000080824 HSP90AA1 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.97715 View
ENSG00000104885 DOT1L ENSG00000150991 UBC H. sapiens SDL Slorth 0.974856 View
ENSG00000104885 DOT1L ENSG00000141510 TP53 H. sapiens SDL Slorth 0.973262 View
ENSG00000104885 DOT1L ENSG00000133703 KRAS H. sapiens SSL Slorth 0.97056 View
ENSG00000104885 DOT1L ENSG00000132646 PCNA H. sapiens SDL Slorth 0.967494 View
ENSG00000104885 DOT1L ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.966988 View
ENSG00000005339 CREBBP ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.964738 View
ENSG00000096717 SIRT1 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.963967 View
ENSG00000100030 MAPK1 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.959891 View
ENSG00000101266 CSNK2A1 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.959683 View
ENSG00000096384 HSP90AB1 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.959358 View
ENSG00000002016 RAD52 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.95654 View
ENSG00000012048 BRCA1 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.956305 View
ENSG00000068024 HDAC4 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.955124 View
ENSG00000103275 UBE2I ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.947746 View
ENSG00000104885 DOT1L ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.947106 View
ENSG00000103275 UBE2I ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.9459 View
ENSG00000104885 DOT1L ENSG00000177606 JUN H. sapiens SDL Slorth 0.941847 View
ENSG00000091831 ESR1 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.941712 View
ENSG00000104885 DOT1L ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.939986 View
ENSG00000100030 MAPK1 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.939811 View
ENSG00000104885 DOT1L ENSG00000197299 BLM H. sapiens SDL Slorth 0.938387 View
ENSG00000104885 DOT1L ENSG00000169083 AR H. sapiens SDL Slorth 0.937291 View
ENSG00000104885 DOT1L ENSG00000173039 RELA H. sapiens SDL Slorth 0.937282 View
ENSG00000104885 DOT1L ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.935494 View
ENSG00000104885 DOT1L ENSG00000149311 ATM H. sapiens SDL Slorth 0.934962 View
ENSG00000104885 DOT1L ENSG00000149554 CHEK1 H. sapiens SDL Slorth 0.934402 View
ENSG00000101412 E2F1 ENSG00000104885 DOT1L H. sapiens SDL Slorth 0.932703 View
ENSG00000097046 CDC7 ENSG00000104885 DOT1L H. sapiens SSL Slorth 0.931934 View
ENSG00000104885 DOT1L ENSG00000109670 FBXW7 H. sapiens SSL Slorth 0.928506 View