DOT1L - FBXW7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DOT1L	ENSG00000104885	No diseases in record	No drugs in record	DNA binding protein binding histone-lysine N-methyltransferase activity histone methyltransferase activity (H3-K79 specific) histone methyltransferase activity	DOT1 (S. cerevisiae) gpp (D. melanogaster)
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)