LEF1

ENSG00000138795 - H. sapiens

Pathways

Go term Description
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008301 DNA binding, bending
GO:0030284 estrogen receptor activity
GO:0030331 estrogen receptor binding
GO:0035326 enhancer binding
GO:0042393 histone binding
GO:0042826 histone deacetylase binding
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0045295 gamma-catenin binding
GO:0070016 armadillo repeat domain binding
GO:0070742 C2H2 zinc finger domain binding

Drugs

No drugs in record

Diseases

Disease Name
B-ALL
T-ALL
eyelid sebaceous carcinoma
AML
lymphomas

Orthologs

Gene Organism
pop-1 C. elegans
pan D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000089157 RPLP0 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.911582 View
ENSG00000101966 XIAP ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.911426 View
ENSG00000123908 AGO2 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.911049 View
ENSG00000109971 HSPA8 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.910632 View
ENSG00000111276 CDKN1B ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.909564 View
ENSG00000103035 PSMD7 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.909546 View
ENSG00000116030 SUMO1 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.909404 View
ENSG00000101412 E2F1 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.909401 View
ENSG00000100519 PSMC6 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.909219 View
ENSG00000108671 PSMD11 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.908286 View
ENSG00000138376 BARD1 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.907719 View
ENSG00000134086 VHL ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.907022 View
ENSG00000094916 CBX5 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.906875 View
ENSG00000105810 CDK6 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.905956 View
ENSG00000134982 APC ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.904965 View
ENSG00000138795 LEF1 ENSG00000143106 PSMA5 H. sapiens SDL Slorth 0.904922 View
ENSG00000070010 UFD1L ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.90461 View
ENSG00000138795 LEF1 ENSG00000165280 VCP H. sapiens SDL Slorth 0.904312 View
ENSG00000116251 RPL22 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.902018 View
ENSG00000008018 PSMB1 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.900737 View
ENSG00000113575 PPP2CA ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.900644 View
ENSG00000131759 RARA ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.899453 View
ENSG00000114166 KAT2B ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.89923 View
ENSG00000138795 LEF1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.897577 View
ENSG00000136807 CDK9 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.895092 View
ENSG00000128908 INO80 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.894766 View
ENSG00000113558 SKP1 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.891551 View
ENSG00000005339 CREBBP ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.890774 View
ENSG00000133316 WDR74 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.890757 View
ENSG00000113721 PDGFRB ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.889023 View
ENSG00000100906 NFKBIA ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.887709 View
ENSG00000069869 NEDD4 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.886508 View
ENSG00000100644 HIF1A ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.884472 View
ENSG00000105810 CDK6 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.884469 View
ENSG00000137486 ARRB1 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.883378 View
ENSG00000130726 TRIM28 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.879389 View
ENSG00000117133 RPF1 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.878652 View
ENSG00000135341 MAP3K7 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.878508 View
ENSG00000075624 ACTB ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.878483 View
ENSG00000055130 CUL1 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.877979 View