RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000175793 SFN H. sapiens SSL Slorth 0.96775 View
ENSG00000123612 ACVR1C ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967739 View
ENSG00000132155 RAF1 ENSG00000162924 REL H. sapiens SDL Slorth 0.967733 View
ENSG00000132155 RAF1 ENSG00000153487 ING1 H. sapiens SSL Slorth 0.967717 View
ENSG00000132155 RAF1 ENSG00000157456 CCNB2 H. sapiens SDL Slorth 0.967716 View
ENSG00000011132 APBA3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967706 View
ENSG00000132155 RAF1 ENSG00000198742 SMURF1 H. sapiens SDL Slorth 0.967683 View
ENSG00000132155 RAF1 ENSG00000159720 ATP6V0D1 H. sapiens SDL Slorth 0.967674 View
ENSG00000118680 MYL12B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967655 View
ENSG00000005339 CREBBP ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967644 View
ENSG00000101146 RAE1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.967634 View
ENSG00000105329 TGFB1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967632 View
ENSG00000132155 RAF1 ENSG00000155304 HSPA13 H. sapiens SDL Slorth 0.967607 View
ENSG00000132155 RAF1 ENSG00000180370 PAK2 H. sapiens SDL Slorth 0.967519 View
ENSG00000132155 RAF1 ENSG00000196470 SIAH1 H. sapiens SDL Slorth 0.967516 View
ENSG00000087263 OGFOD1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967466 View
ENSG00000132155 RAF1 ENSG00000177731 FLII H. sapiens SDL Slorth 0.967458 View
ENSG00000132155 RAF1 ENSG00000157933 SKI H. sapiens SSL Slorth 0.967448 View
ENSG00000132155 RAF1 ENSG00000198909 MAP3K3 H. sapiens SSL Slorth 0.967383 View
ENSG00000071242 RPS6KA2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967347 View
ENSG00000132155 RAF1 ENSG00000144852 NR1I2 H. sapiens SDL Slorth 0.967344 View
ENSG00000092820 EZR ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967256 View
ENSG00000132155 RAF1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.967234 View
ENSG00000132155 RAF1 ENSG00000168906 MAT2A H. sapiens SDL Slorth 0.967231 View
ENSG00000064489 BORCS8-MEF2B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967215 View
ENSG00000132155 RAF1 ENSG00000133056 PIK3C2B H. sapiens SDL Slorth 0.96713 View
ENSG00000132155 RAF1 ENSG00000142453 CARM1 H. sapiens SSL Slorth 0.96712 View
ENSG00000085382 HACE1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967093 View
ENSG00000129521 EGLN3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967066 View
ENSG00000132155 RAF1 ENSG00000139719 VPS33A H. sapiens SDL Slorth 0.967026 View
ENSG00000130037 KCNA5 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.967007 View
ENSG00000132155 RAF1 ENSG00000162736 NCSTN H. sapiens SSL Slorth 0.966946 View
ENSG00000130669 PAK4 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.966935 View
ENSG00000132155 RAF1 ENSG00000151532 VTI1A H. sapiens SDL Slorth 0.966931 View
ENSG00000121691 CAT ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.966924 View
ENSG00000117650 NEK2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.966919 View
ENSG00000132155 RAF1 ENSG00000137807 KIF23 H. sapiens SDL Slorth 0.966913 View
ENSG00000132155 RAF1 ENSG00000141480 ARRB2 H. sapiens SDL Slorth 0.966859 View
ENSG00000132155 RAF1 ENSG00000154928 EPHB1 H. sapiens SDL Slorth 0.966858 View
ENSG00000132155 RAF1 ENSG00000204843 DCTN1 H. sapiens SDL Slorth 0.966839 View