RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000143093 STRIP1 H. sapiens SDL Slorth 0.969264 View
ENSG00000132155 RAF1 ENSG00000150457 LATS2 H. sapiens SDL Slorth 0.969256 View
ENSG00000132155 RAF1 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.96924 View
ENSG00000132155 RAF1 ENSG00000162236 STX5 H. sapiens SDL Slorth 0.969226 View
ENSG00000096696 DSP ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.969186 View
ENSG00000112246 SIM1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.96917 View
ENSG00000132155 RAF1 ENSG00000173020 GRK2 H. sapiens SDL Slorth 0.96908 View
ENSG00000079819 EPB41L2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.969032 View
ENSG00000102225 CDK16 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.968985 View
ENSG00000132155 RAF1 ENSG00000198719 DLL1 H. sapiens SDL Slorth 0.968944 View
ENSG00000132155 RAF1 ENSG00000169439 SDC2 H. sapiens SDL Slorth 0.96894 View
ENSG00000082641 NFE2L1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.968923 View
ENSG00000100596 SPTLC2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.968921 View
ENSG00000132155 RAF1 ENSG00000198353 HOXC4 H. sapiens SDL Slorth 0.968916 View
ENSG00000132155 RAF1 ENSG00000143476 DTL H. sapiens SSL Slorth 0.968846 View
ENSG00000132155 RAF1 ENSG00000168283 BMI1 H. sapiens SSL Slorth 0.968685 View
ENSG00000126785 RHOJ ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.968661 View
ENSG00000132155 RAF1 ENSG00000185236 RAB11B H. sapiens SDL Slorth 0.968651 View
ENSG00000132155 RAF1 ENSG00000204842 ATXN2 H. sapiens SDL Slorth 0.968647 View
ENSG00000132155 RAF1 ENSG00000176444 CLK2 H. sapiens SDL Slorth 0.968627 View
ENSG00000132155 RAF1 ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.96862 View
ENSG00000132155 RAF1 ENSG00000184304 PRKD1 H. sapiens SDL Slorth 0.968617 View
ENSG00000132155 RAF1 ENSG00000173757 STAT5B H. sapiens SDL Slorth 0.968613 View
ENSG00000132155 RAF1 ENSG00000156970 BUB1B H. sapiens SSL Slorth 0.968607 View
ENSG00000132155 RAF1 ENSG00000166974 MAPRE2 H. sapiens SDL Slorth 0.968418 View
ENSG00000132155 RAF1 ENSG00000164116 GUCY1A3 H. sapiens SDL Slorth 0.968416 View
ENSG00000089094 KDM2B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.968384 View
ENSG00000132155 RAF1 ENSG00000184557 SOCS3 H. sapiens SDL Slorth 0.968376 View
ENSG00000115267 IFIH1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.968258 View
ENSG00000100721 TCL1A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.968186 View
ENSG00000132155 RAF1 ENSG00000164045 CDC25A H. sapiens SDL Slorth 0.968184 View
ENSG00000132155 RAF1 ENSG00000140464 PML H. sapiens SDL Slorth 0.968099 View
ENSG00000132155 RAF1 ENSG00000170759 KIF5B H. sapiens SDL Slorth 0.968068 View
ENSG00000121966 CXCR4 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.968061 View
ENSG00000132155 RAF1 ENSG00000183814 LIN9 H. sapiens SDL Slorth 0.968058 View
ENSG00000132155 RAF1 ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.968024 View
ENSG00000132155 RAF1 ENSG00000132471 WBP2 H. sapiens SDL Slorth 0.968013 View
ENSG00000132155 RAF1 ENSG00000143970 ASXL2 H. sapiens SDL Slorth 0.968013 View
ENSG00000132155 RAF1 ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.967927 View
ENSG00000132155 RAF1 ENSG00000132341 RAN H. sapiens SSL Slorth 0.967926 View