RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000170881 RNF139 H. sapiens SDL Slorth 0.965817 View
ENSG00000132155 RAF1 ENSG00000205302 SNX2 H. sapiens SDL Slorth 0.965788 View
ENSG00000132155 RAF1 ENSG00000135486 HNRNPA1 H. sapiens SDL Slorth 0.965774 View
ENSG00000114738 MAPKAPK3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.965725 View
ENSG00000132155 RAF1 ENSG00000147162 OGT H. sapiens SSL Slorth 0.965703 View
ENSG00000124232 RBPJL ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.965702 View
ENSG00000107295 SH3GL2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.9657 View
ENSG00000132155 RAF1 ENSG00000198554 WDHD1 H. sapiens SDL Slorth 0.965682 View
ENSG00000132155 RAF1 ENSG00000147010 SH3KBP1 H. sapiens SSL Slorth 0.965658 View
ENSG00000132155 RAF1 ENSG00000163602 RYBP H. sapiens SDL Slorth 0.965635 View
ENSG00000132155 RAF1 ENSG00000173402 DAG1 H. sapiens SDL Slorth 0.965633 View
ENSG00000132155 RAF1 ENSG00000142949 PTPRF H. sapiens SDL Slorth 0.965616 View
ENSG00000132155 RAF1 ENSG00000184009 ACTG1 H. sapiens SDL Slorth 0.965595 View
ENSG00000132155 RAF1 ENSG00000136810 TXN H. sapiens SSL Slorth 0.965584 View
ENSG00000090432 MUL1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.965561 View
ENSG00000132155 RAF1 ENSG00000185104 FAF1 H. sapiens SDL Slorth 0.965559 View
ENSG00000070404 FSTL3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.965528 View
ENSG00000132155 RAF1 ENSG00000198793 MTOR H. sapiens SSL Slorth 0.965502 View
ENSG00000096717 SIRT1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.965402 View
ENSG00000122592 HOXA7 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.965372 View
ENSG00000106689 LHX2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.965372 View
ENSG00000063438 AHRR ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.965372 View
ENSG00000132155 RAF1 ENSG00000149084 HSD17B12 H. sapiens SDL Slorth 0.965353 View
ENSG00000132155 RAF1 ENSG00000180198 RCC1 H. sapiens SSL Slorth 0.96535 View
ENSG00000132155 RAF1 ENSG00000164924 YWHAZ H. sapiens SDL Slorth 0.965344 View
ENSG00000131475 VPS25 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.965211 View
ENSG00000132155 RAF1 ENSG00000166266 CUL5 H. sapiens SDL Slorth 0.96521 View
ENSG00000004700 RECQL ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.965198 View
ENSG00000132155 RAF1 ENSG00000182255 KCNA4 H. sapiens SDL Slorth 0.96516 View
ENSG00000099875 MKNK2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.965093 View
ENSG00000132155 RAF1 ENSG00000185513 L3MBTL1 H. sapiens SDL Slorth 0.965006 View
ENSG00000132155 RAF1 ENSG00000198380 GFPT1 H. sapiens SDL Slorth 0.964994 View
ENSG00000132155 RAF1 ENSG00000154229 PRKCA H. sapiens SDL Slorth 0.964979 View
ENSG00000132155 RAF1 ENSG00000239857 GET4 H. sapiens SSL Slorth 0.964956 View
ENSG00000005249 PRKAR2B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.964923 View
ENSG00000131899 LLGL1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.964898 View
ENSG00000013441 CLK1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.96483 View
ENSG00000127314 RAP1B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.964809 View
ENSG00000132155 RAF1 ENSG00000169967 MAP3K2 H. sapiens SSL Slorth 0.964773 View
ENSG00000127511 SIN3B ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.964772 View