RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.971663 View
ENSG00000132155 RAF1 ENSG00000175745 NR2F1 H. sapiens SDL Slorth 0.971661 View
ENSG00000132155 RAF1 ENSG00000167461 RAB8A H. sapiens SDL Slorth 0.97166 View
ENSG00000132155 RAF1 ENSG00000165637 VDAC2 H. sapiens SDL Slorth 0.971651 View
ENSG00000092529 CAPN3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.971603 View
ENSG00000132155 RAF1 ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.971584 View
ENSG00000100614 PPM1A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.971553 View
ENSG00000132155 RAF1 ENSG00000136450 SRSF1 H. sapiens SSL Slorth 0.971492 View
ENSG00000132155 RAF1 ENSG00000186432 KPNA4 H. sapiens SDL Slorth 0.971479 View
ENSG00000132155 RAF1 ENSG00000239900 ADSL H. sapiens SDL Slorth 0.971437 View
ENSG00000132155 RAF1 ENSG00000177054 ZDHHC13 H. sapiens SDL Slorth 0.971437 View
ENSG00000132155 RAF1 ENSG00000165801 ARHGEF40 H. sapiens SDL Slorth 0.971437 View
ENSG00000132155 RAF1 ENSG00000136261 BZW2 H. sapiens SDL Slorth 0.971437 View
ENSG00000132155 RAF1 ENSG00000160746 ANO10 H. sapiens SDL Slorth 0.971437 View
ENSG00000132155 RAF1 ENSG00000163932 PRKCD H. sapiens SSL Slorth 0.971426 View
ENSG00000132155 RAF1 ENSG00000169045 HNRNPH1 H. sapiens SSL Slorth 0.971418 View
ENSG00000132155 RAF1 ENSG00000132170 PPARG H. sapiens SSL Slorth 0.971344 View
ENSG00000008196 TFAP2B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.971274 View
ENSG00000132155 RAF1 ENSG00000133639 BTG1 H. sapiens SDL Slorth 0.971265 View
ENSG00000132155 RAF1 ENSG00000196712 NF1 H. sapiens SDL Slorth 0.971254 View
ENSG00000124207 CSE1L ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.971243 View
ENSG00000101868 POLA1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.971211 View
ENSG00000125618 PAX8 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.971204 View
ENSG00000106459 NRF1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.971198 View
ENSG00000132155 RAF1 ENSG00000177189 RPS6KA3 H. sapiens SDL Slorth 0.971171 View
ENSG00000132155 RAF1 ENSG00000141985 SH3GL1 H. sapiens SDL Slorth 0.971164 View
ENSG00000132155 RAF1 ENSG00000185359 HGS H. sapiens SSL Slorth 0.971106 View
ENSG00000102145 GATA1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.971095 View
ENSG00000115507 OTX1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.971085 View
ENSG00000118985 ELL2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.971076 View
ENSG00000132155 RAF1 ENSG00000198258 UBL5 H. sapiens SDL Slorth 0.971075 View
ENSG00000132155 RAF1 ENSG00000164070 HSPA4L H. sapiens SDL Slorth 0.97107 View
ENSG00000132155 RAF1 ENSG00000198492 YTHDF2 H. sapiens SDL Slorth 0.97107 View
ENSG00000132155 RAF1 ENSG00000143545 RAB13 H. sapiens SDL Slorth 0.97107 View
ENSG00000132155 RAF1 ENSG00000138646 HERC5 H. sapiens SDL Slorth 0.97107 View
ENSG00000132155 RAF1 ENSG00000188042 ARL4C H. sapiens SDL Slorth 0.97107 View
ENSG00000132155 RAF1 ENSG00000162616 DNAJB4 H. sapiens SDL Slorth 0.97107 View
ENSG00000132155 RAF1 ENSG00000170385 SLC30A1 H. sapiens SDL Slorth 0.97107 View
ENSG00000132155 RAF1 ENSG00000154767 XPC H. sapiens SDL Slorth 0.971035 View
ENSG00000132155 RAF1 ENSG00000136877 FPGS H. sapiens SDL Slorth 0.970975 View