RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000141736 ERBB2 H. sapiens SDL Slorth 0.973372 View
ENSG00000132155 RAF1 ENSG00000175766 EIF4E1B H. sapiens SDL Slorth 0.973324 View
ENSG00000105204 DYRK1B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.973203 View
ENSG00000132155 RAF1 ENSG00000214517 PPME1 H. sapiens SDL Slorth 0.973186 View
ENSG00000106003 LFNG ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.97316 View
ENSG00000124145 SDC4 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.973158 View
ENSG00000132155 RAF1 ENSG00000137497 NUMA1 H. sapiens SDL Slorth 0.973152 View
ENSG00000132155 RAF1 ENSG00000155508 CNOT8 H. sapiens SDL Slorth 0.973143 View
ENSG00000132155 RAF1 ENSG00000145555 MYO10 H. sapiens SDL Slorth 0.973075 View
ENSG00000132155 RAF1 ENSG00000163743 RCHY1 H. sapiens SSL Slorth 0.973066 View
ENSG00000101349 PAK5 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.973065 View
ENSG00000087470 DNM1L ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.973048 View
ENSG00000132155 RAF1 ENSG00000134982 APC H. sapiens SSL Slorth 0.972995 View
ENSG00000132155 RAF1 ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.972991 View
ENSG00000092421 SEMA6A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.972966 View
ENSG00000126583 PRKCG ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.972962 View
ENSG00000132155 RAF1 ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.97294 View
ENSG00000132155 RAF1 ENSG00000185615 PDIA2 H. sapiens SDL Slorth 0.972928 View
ENSG00000132155 RAF1 ENSG00000167986 DDB1 H. sapiens SSL Slorth 0.972926 View
ENSG00000087510 TFAP2C ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.972892 View
ENSG00000132155 RAF1 ENSG00000213465 ARL2 H. sapiens SDL Slorth 0.972861 View
ENSG00000132155 RAF1 ENSG00000136492 BRIP1 H. sapiens SDL Slorth 0.972837 View
ENSG00000080345 RIF1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.972727 View
ENSG00000132155 RAF1 ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.972712 View
ENSG00000132155 RAF1 ENSG00000169032 MAP2K1 H. sapiens SDL Slorth 0.972706 View
ENSG00000132155 RAF1 ENSG00000198901 PRC1 H. sapiens SDL Slorth 0.97267 View
ENSG00000132155 RAF1 ENSG00000145386 CCNA2 H. sapiens SDL Slorth 0.972655 View
ENSG00000132155 RAF1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.972633 View
ENSG00000132155 RAF1 ENSG00000170345 FOS H. sapiens SSL Slorth 0.972592 View
ENSG00000132155 RAF1 ENSG00000197969 VPS13A H. sapiens SDL Slorth 0.972583 View
ENSG00000132155 RAF1 ENSG00000166128 RAB8B H. sapiens SDL Slorth 0.972583 View
ENSG00000132155 RAF1 ENSG00000136286 MYO1G H. sapiens SDL Slorth 0.972583 View
ENSG00000132155 RAF1 ENSG00000144746 ARL6IP5 H. sapiens SDL Slorth 0.972583 View
ENSG00000132155 RAF1 ENSG00000138138 ATAD1 H. sapiens SDL Slorth 0.972583 View
ENSG00000132155 RAF1 ENSG00000134644 PUM1 H. sapiens SDL Slorth 0.972583 View
ENSG00000132155 RAF1 ENSG00000139514 SLC7A1 H. sapiens SDL Slorth 0.972583 View
ENSG00000132155 RAF1 ENSG00000198218 QRICH1 H. sapiens SDL Slorth 0.972583 View
ENSG00000132155 RAF1 ENSG00000182220 ATP6AP2 H. sapiens SDL Slorth 0.972583 View
ENSG00000132155 RAF1 ENSG00000189241 TSPYL1 H. sapiens SDL Slorth 0.972583 View
ENSG00000132155 RAF1 ENSG00000140263 SORD H. sapiens SDL Slorth 0.972583 View