ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000117461 PIK3R3 H. sapiens SSL Slorth 0.833197 View
ENSG00000091831 ESR1 ENSG00000175582 RAB6A H. sapiens SSL Slorth 0.833026 View
ENSG00000091831 ESR1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.833002 View
ENSG00000091831 ESR1 ENSG00000168818 STX18 H. sapiens SSL Slorth 0.833 View
ENSG00000091831 ESR1 ENSG00000196083 IL1RAP H. sapiens SSL Slorth 0.83291 View
ENSG00000091831 ESR1 ENSG00000185591 SP1 H. sapiens SSL Slorth 0.832813 View
ENSG00000091831 ESR1 ENSG00000106366 SERPINE1 H. sapiens SSL Slorth 0.83255 View
ENSG00000091831 ESR1 ENSG00000135250 SRPK2 H. sapiens SSL Slorth 0.832467 View
ENSG00000091831 ESR1 ENSG00000147130 ZMYM3 H. sapiens SSL Slorth 0.832343 View
ENSG00000091831 ESR1 ENSG00000137265 IRF4 H. sapiens SSL Slorth 0.832073 View
ENSG00000091831 ESR1 ENSG00000106299 WASL H. sapiens SSL Slorth 0.832029 View
ENSG00000091831 ESR1 ENSG00000198053 SIRPA H. sapiens SSL Slorth 0.832008 View
ENSG00000091831 ESR1 ENSG00000122180 MYOG H. sapiens SSL Slorth 0.831941 View
ENSG00000091831 ESR1 ENSG00000204086 RPA4 H. sapiens SSL Slorth 0.831892 View
ENSG00000091831 ESR1 ENSG00000163166 IWS1 H. sapiens SSL Slorth 0.831834 View
ENSG00000091831 ESR1 ENSG00000182208 MOB2 H. sapiens SSL Slorth 0.831663 View
ENSG00000091831 ESR1 ENSG00000144852 NR1I2 H. sapiens SSL Slorth 0.831506 View
ENSG00000091831 ESR1 ENSG00000114302 PRKAR2A H. sapiens SSL Slorth 0.831252 View
ENSG00000091831 ESR1 ENSG00000152104 PTPN14 H. sapiens SSL Slorth 0.830979 View
ENSG00000091831 ESR1 ENSG00000105723 GSK3A H. sapiens SSL Slorth 0.830636 View
ENSG00000091831 ESR1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.83061 View
ENSG00000091831 ESR1 ENSG00000155868 MED7 H. sapiens SSL Slorth 0.830495 View
ENSG00000091831 ESR1 ENSG00000100632 ERH H. sapiens SSL Slorth 0.830456 View
ENSG00000091831 ESR1 ENSG00000185009 AP3M1 H. sapiens SSL Slorth 0.830366 View
ENSG00000091831 ESR1 ENSG00000130332 LSM7 H. sapiens SSL Slorth 0.830359 View
ENSG00000091831 ESR1 ENSG00000139220 PPFIA2 H. sapiens SSL Slorth 0.830293 View
ENSG00000091831 ESR1 ENSG00000143322 ABL2 H. sapiens SSL Slorth 0.830292 View
ENSG00000091831 ESR1 ENSG00000135999 EPC2 H. sapiens SSL Slorth 0.830211 View
ENSG00000091831 ESR1 ENSG00000175324 LSM1 H. sapiens SSL Slorth 0.830127 View
ENSG00000091831 ESR1 ENSG00000103222 ABCC1 H. sapiens SSL Slorth 0.829985 View
ENSG00000091831 ESR1 ENSG00000182199 SHMT2 H. sapiens SSL Slorth 0.829825 View
ENSG00000091831 ESR1 ENSG00000213465 ARL2 H. sapiens SSL Slorth 0.829803 View
ENSG00000091831 ESR1 ENSG00000130811 EIF3G H. sapiens SSL Slorth 0.829778 View
ENSG00000091831 ESR1 ENSG00000155363 MOV10 H. sapiens SSL Slorth 0.829766 View
ENSG00000091831 ESR1 ENSG00000114978 MOB1A H. sapiens SSL Slorth 0.82967 View
ENSG00000091831 ESR1 ENSG00000105245 NUMBL H. sapiens SSL Slorth 0.829546 View
ENSG00000091831 ESR1 ENSG00000167460 TPM4 H. sapiens SSL Slorth 0.829488 View
ENSG00000091831 ESR1 ENSG00000182866 LCK H. sapiens SSL Slorth 0.82948 View
ENSG00000091831 ESR1 ENSG00000124198 ARFGEF2 H. sapiens SSL Slorth 0.829328 View
ENSG00000091831 ESR1 ENSG00000188191 PRKAR1B H. sapiens SSL Slorth 0.829328 View