ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000104881 PPP1R13L H. sapiens SSL Slorth 0.843142 View
ENSG00000091831 ESR1 ENSG00000197122 SRC H. sapiens SSL Slorth 0.843107 View
ENSG00000091831 ESR1 ENSG00000185624 P4HB H. sapiens SSL Slorth 0.842994 View
ENSG00000091831 ESR1 ENSG00000110107 PRPF19 H. sapiens SSL Slorth 0.84298 View
ENSG00000091831 ESR1 ENSG00000187323 DCC H. sapiens SSL Slorth 0.842821 View
ENSG00000091831 ESR1 ENSG00000107672 NSMCE4A H. sapiens SSL Slorth 0.842809 View
ENSG00000091831 ESR1 ENSG00000107404 DVL1 H. sapiens SSL Slorth 0.842749 View
ENSG00000091831 ESR1 ENSG00000100084 HIRA H. sapiens SSL Slorth 0.842549 View
ENSG00000091831 ESR1 ENSG00000164815 ORC5 H. sapiens SSL Slorth 0.842349 View
ENSG00000091831 ESR1 ENSG00000196792 STRN3 H. sapiens SSL Slorth 0.842305 View
ENSG00000091831 ESR1 ENSG00000108590 MED31 H. sapiens SSL Slorth 0.842214 View
ENSG00000091831 ESR1 ENSG00000157020 SEC13 H. sapiens SSL Slorth 0.842211 View
ENSG00000091831 ESR1 ENSG00000164548 TRA2A H. sapiens SSL Slorth 0.842145 View
ENSG00000091831 ESR1 ENSG00000100387 RBX1 H. sapiens SSL Slorth 0.842079 View
ENSG00000091831 ESR1 ENSG00000107104 KANK1 H. sapiens SSL Slorth 0.842072 View
ENSG00000091831 ESR1 ENSG00000156603 MED19 H. sapiens SSL Slorth 0.842011 View
ENSG00000091831 ESR1 ENSG00000114742 WDR48 H. sapiens SSL Slorth 0.841857 View
ENSG00000091831 ESR1 ENSG00000118058 KMT2A H. sapiens SSL Slorth 0.841848 View
ENSG00000091831 ESR1 ENSG00000213066 FGFR1OP H. sapiens SSL Slorth 0.841792 View
ENSG00000091831 ESR1 ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.841641 View
ENSG00000091831 ESR1 ENSG00000145375 SPATA5 H. sapiens SSL Slorth 0.841575 View
ENSG00000091831 ESR1 ENSG00000170881 RNF139 H. sapiens SSL Slorth 0.841409 View
ENSG00000091831 ESR1 ENSG00000171148 TADA3 H. sapiens SSL Slorth 0.841389 View
ENSG00000091831 ESR1 ENSG00000162961 DPY30 H. sapiens SSL Slorth 0.841354 View
ENSG00000091831 ESR1 ENSG00000189403 HMGB1 H. sapiens SSL Slorth 0.841172 View
ENSG00000091831 ESR1 ENSG00000125733 TRIP10 H. sapiens SSL Slorth 0.841074 View
ENSG00000091831 ESR1 ENSG00000144935 TRPC1 H. sapiens SSL Slorth 0.841012 View
ENSG00000091831 ESR1 ENSG00000182621 PLCB1 H. sapiens SSL Slorth 0.840825 View
ENSG00000091831 ESR1 ENSG00000110075 PPP6R3 H. sapiens SSL Slorth 0.8408 View
ENSG00000091831 ESR1 ENSG00000172071 EIF2AK3 H. sapiens SSL Slorth 0.840699 View
ENSG00000091831 ESR1 ENSG00000174672 BRSK2 H. sapiens SSL Slorth 0.840689 View
ENSG00000091831 ESR1 ENSG00000103363 TCEB2 H. sapiens SSL Slorth 0.840638 View
ENSG00000091831 ESR1 ENSG00000182541 LIMK2 H. sapiens SSL Slorth 0.840569 View
ENSG00000091831 ESR1 ENSG00000100461 RBM23 H. sapiens SSL Slorth 0.840472 View
ENSG00000091831 ESR1 ENSG00000157540 DYRK1A H. sapiens SSL Slorth 0.840302 View
ENSG00000091831 ESR1 ENSG00000133302 SLF1 H. sapiens SSL Slorth 0.840121 View
ENSG00000091831 ESR1 ENSG00000153233 PTPRR H. sapiens SSL Slorth 0.840082 View
ENSG00000091831 ESR1 ENSG00000156802 ATAD2 H. sapiens SSL Slorth 0.839953 View
ENSG00000091831 ESR1 ENSG00000111199 TRPV4 H. sapiens SSL Slorth 0.83988 View
ENSG00000091831 ESR1 ENSG00000104365 IKBKB H. sapiens SSL Slorth 0.839824 View