ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000113141 IK H. sapiens SDL Slorth 0.902796 View
ENSG00000091831 ESR1 ENSG00000155508 CNOT8 H. sapiens SSL Slorth 0.902723 View
ENSG00000091831 ESR1 ENSG00000221914 PPP2R2A H. sapiens SSL Slorth 0.902716 View
ENSG00000091831 ESR1 ENSG00000105254 TBCB H. sapiens SSL Slorth 0.902454 View
ENSG00000091831 ESR1 ENSG00000100138 SNU13 H. sapiens SDL Slorth 0.902423 View
ENSG00000091831 ESR1 ENSG00000173542 MOB1B H. sapiens SSL Slorth 0.90241 View
ENSG00000091831 ESR1 ENSG00000143379 SETDB1 H. sapiens SSL Slorth 0.902163 View
ENSG00000091831 ESR1 ENSG00000122691 TWIST1 H. sapiens SSL Slorth 0.902153 View
ENSG00000091831 ESR1 ENSG00000183161 FANCF H. sapiens SDL Slorth 0.902111 View
ENSG00000065613 SLK ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.90204 View
ENSG00000091831 ESR1 ENSG00000198668 CALM1 H. sapiens SSL Slorth 0.902 View
ENSG00000091831 ESR1 ENSG00000163914 RHO H. sapiens SSL Slorth 0.901874 View
ENSG00000091831 ESR1 ENSG00000168397 ATG4B H. sapiens SSL Slorth 0.901715 View
ENSG00000091831 ESR1 ENSG00000107954 NEURL1 H. sapiens SDL Slorth 0.901677 View
ENSG00000091831 ESR1 ENSG00000163947 ARHGEF3 H. sapiens SDL Slorth 0.901604 View
ENSG00000091831 ESR1 ENSG00000130589 HELZ2 H. sapiens SDL Slorth 0.901548 View
ENSG00000091831 ESR1 ENSG00000179776 CDH5 H. sapiens SSL Slorth 0.901411 View
ENSG00000091831 ESR1 ENSG00000261832 RP11-435I10.4 H. sapiens SDL Slorth 0.9013 View
ENSG00000078061 ARAF ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.901254 View
ENSG00000091831 ESR1 ENSG00000164597 COG5 H. sapiens SSL Slorth 0.901196 View
ENSG00000091831 ESR1 ENSG00000130939 UBE4B H. sapiens SDL Slorth 0.901195 View
ENSG00000091831 ESR1 ENSG00000166595 FAM96B H. sapiens SDL Slorth 0.90116 View
ENSG00000091831 ESR1 ENSG00000122025 FLT3 H. sapiens SSL Slorth 0.901102 View
ENSG00000091831 ESR1 ENSG00000123600 METTL8 H. sapiens SDL Slorth 0.901078 View
ENSG00000091831 ESR1 ENSG00000148229 POLE3 H. sapiens SSL Slorth 0.901037 View
ENSG00000091831 ESR1 ENSG00000105438 KDELR1 H. sapiens SDL Slorth 0.901017 View
ENSG00000091831 ESR1 ENSG00000164754 RAD21 H. sapiens SSL Slorth 0.900992 View
ENSG00000091831 ESR1 ENSG00000146425 DYNLT1 H. sapiens SSL Slorth 0.900698 View
ENSG00000091831 ESR1 ENSG00000168421 RHOH H. sapiens SDL Slorth 0.900554 View
ENSG00000091831 ESR1 ENSG00000183020 AP2A2 H. sapiens SSL Slorth 0.900354 View
ENSG00000091831 ESR1 ENSG00000178184 PARD6G H. sapiens SSL Slorth 0.900275 View
ENSG00000091831 ESR1 ENSG00000152818 UTRN H. sapiens SSL Slorth 0.900257 View
ENSG00000091831 ESR1 ENSG00000173020 GRK2 H. sapiens SSL Slorth 0.900253 View
ENSG00000091831 ESR1 ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.900213 View
ENSG00000005339 CREBBP ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.900041 View
ENSG00000084774 CAD ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.900037 View
ENSG00000091831 ESR1 ENSG00000126226 PCID2 H. sapiens SSL Slorth 0.899881 View
ENSG00000091831 ESR1 ENSG00000105397 TYK2 H. sapiens SSL Slorth 0.899751 View
ENSG00000091831 ESR1 ENSG00000106799 TGFBR1 H. sapiens SSL Slorth 0.899666 View
ENSG00000091831 ESR1 ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.899626 View