ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000185009 AP3M1 H. sapiens SDL Slorth 0.908865 View
ENSG00000091831 ESR1 ENSG00000115738 ID2 H. sapiens SSL Slorth 0.908818 View
ENSG00000091831 ESR1 ENSG00000198088 NUP62CL H. sapiens SDL Slorth 0.908792 View
ENSG00000091831 ESR1 ENSG00000095015 MAP3K1 H. sapiens SSL Slorth 0.908785 View
ENSG00000091831 ESR1 ENSG00000165699 TSC1 H. sapiens SSL Slorth 0.908733 View
ENSG00000091831 ESR1 ENSG00000148200 NR6A1 H. sapiens SDL Slorth 0.908576 View
ENSG00000091831 ESR1 ENSG00000166974 MAPRE2 H. sapiens SSL Slorth 0.908546 View
ENSG00000091831 ESR1 ENSG00000178188 SH2B1 H. sapiens SSL Slorth 0.908419 View
ENSG00000091831 ESR1 ENSG00000155974 GRIP1 H. sapiens SSL Slorth 0.90831 View
ENSG00000091831 ESR1 ENSG00000168214 RBPJ H. sapiens SSL Slorth 0.908271 View
ENSG00000091831 ESR1 ENSG00000166233 ARIH1 H. sapiens SDL Slorth 0.908223 View
ENSG00000066322 ELOVL1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.908204 View
ENSG00000091831 ESR1 ENSG00000130024 PHF10 H. sapiens SSL Slorth 0.908079 View
ENSG00000091831 ESR1 ENSG00000178999 AURKB H. sapiens SSL Slorth 0.908003 View
ENSG00000091831 ESR1 ENSG00000167216 KATNAL2 H. sapiens SDL Slorth 0.907979 View
ENSG00000091831 ESR1 ENSG00000141084 RANBP10 H. sapiens SDL Slorth 0.907925 View
ENSG00000091831 ESR1 ENSG00000122512 PMS2 H. sapiens SSL Slorth 0.907851 View
ENSG00000091831 ESR1 ENSG00000117859 OSBPL9 H. sapiens SDL Slorth 0.907797 View
ENSG00000091831 ESR1 ENSG00000096063 SRPK1 H. sapiens SSL Slorth 0.907596 View
ENSG00000091831 ESR1 ENSG00000243056 EIF4EBP3 H. sapiens SDL Slorth 0.907557 View
ENSG00000087191 PSMC5 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.907505 View
ENSG00000091831 ESR1 ENSG00000109911 ELP4 H. sapiens SDL Slorth 0.907474 View
ENSG00000091831 ESR1 ENSG00000126368 NR1D1 H. sapiens SDL Slorth 0.907459 View
ENSG00000091831 ESR1 ENSG00000174371 EXO1 H. sapiens SSL Slorth 0.907447 View
ENSG00000091831 ESR1 ENSG00000165525 NEMF H. sapiens SDL Slorth 0.907432 View
ENSG00000091831 ESR1 ENSG00000117592 PRDX6 H. sapiens SSL Slorth 0.907188 View
ENSG00000091831 ESR1 ENSG00000138448 ITGAV H. sapiens SSL Slorth 0.907113 View
ENSG00000091831 ESR1 ENSG00000150672 DLG2 H. sapiens SDL Slorth 0.907106 View
ENSG00000091831 ESR1 ENSG00000178896 EXOSC4 H. sapiens SSL Slorth 0.907085 View
ENSG00000091831 ESR1 ENSG00000132196 HSD17B7 H. sapiens SSL Slorth 0.907036 View
ENSG00000091831 ESR1 ENSG00000177426 TGIF1 H. sapiens SSL Slorth 0.906981 View
ENSG00000091831 ESR1 ENSG00000103510 KAT8 H. sapiens SSL Slorth 0.906918 View
ENSG00000091831 ESR1 ENSG00000106628 POLD2 H. sapiens SSL Slorth 0.906784 View
ENSG00000091831 ESR1 ENSG00000101132 PFDN4 H. sapiens SDL Slorth 0.906772 View
ENSG00000091831 ESR1 ENSG00000186716 BCR H. sapiens SSL Slorth 0.906756 View
ENSG00000091831 ESR1 ENSG00000175766 EIF4E1B H. sapiens SDL Slorth 0.906695 View
ENSG00000091831 ESR1 ENSG00000137764 MAP2K5 H. sapiens SSL Slorth 0.906637 View
ENSG00000091831 ESR1 ENSG00000109911 ELP4 H. sapiens SSL Slorth 0.906585 View
ENSG00000091831 ESR1 ENSG00000102471 NDFIP2 H. sapiens SSL Slorth 0.906561 View
ENSG00000091831 ESR1 ENSG00000138430 OLA1 H. sapiens SSL Slorth 0.906554 View