ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000101057 MYBL2 H. sapiens SSL Slorth 0.91182 View
ENSG00000091831 ESR1 ENSG00000162298 SYVN1 H. sapiens SSL Slorth 0.911719 View
ENSG00000091831 ESR1 ENSG00000107643 MAPK8 H. sapiens SDL Slorth 0.911614 View
ENSG00000091831 ESR1 ENSG00000162231 NXF1 H. sapiens SSL Slorth 0.911569 View
ENSG00000091831 ESR1 ENSG00000115816 CEBPZ H. sapiens SDL Slorth 0.911556 View
ENSG00000091831 ESR1 ENSG00000150593 PDCD4 H. sapiens SSL Slorth 0.911488 View
ENSG00000091831 ESR1 ENSG00000124782 RREB1 H. sapiens SDL Slorth 0.911345 View
ENSG00000091831 ESR1 ENSG00000119392 GLE1 H. sapiens SDL Slorth 0.911312 View
ENSG00000091831 ESR1 ENSG00000113722 CDX1 H. sapiens SSL Slorth 0.911054 View
ENSG00000091831 ESR1 ENSG00000138443 ABI2 H. sapiens SSL Slorth 0.911048 View
ENSG00000091831 ESR1 ENSG00000139112 GABARAPL1 H. sapiens SSL Slorth 0.910955 View
ENSG00000091831 ESR1 ENSG00000163098 BIRC8 H. sapiens SDL Slorth 0.91083 View
ENSG00000091831 ESR1 ENSG00000183161 FANCF H. sapiens SSL Slorth 0.910729 View
ENSG00000091831 ESR1 ENSG00000107201 DDX58 H. sapiens SSL Slorth 0.910632 View
ENSG00000091831 ESR1 ENSG00000133794 ARNTL H. sapiens SSL Slorth 0.910597 View
ENSG00000091831 ESR1 ENSG00000186908 ZDHHC17 H. sapiens SDL Slorth 0.910537 View
ENSG00000091831 ESR1 ENSG00000112335 SNX3 H. sapiens SSL Slorth 0.910501 View
ENSG00000078018 MAP2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.910477 View
ENSG00000073578 SDHA ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.910436 View
ENSG00000051180 RAD51 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.910435 View
ENSG00000091831 ESR1 ENSG00000155959 VBP1 H. sapiens SDL Slorth 0.910394 View
ENSG00000091831 ESR1 ENSG00000143933 CALM2 H. sapiens SDL Slorth 0.910356 View
ENSG00000091831 ESR1 ENSG00000102755 FLT1 H. sapiens SSL Slorth 0.910241 View
ENSG00000091831 ESR1 ENSG00000102753 KPNA3 H. sapiens SDL Slorth 0.910092 View
ENSG00000091831 ESR1 ENSG00000149503 INCENP H. sapiens SSL Slorth 0.910016 View
ENSG00000091831 ESR1 ENSG00000115091 ACTR3 H. sapiens SSL Slorth 0.909816 View
ENSG00000091831 ESR1 ENSG00000126214 KLC1 H. sapiens SSL Slorth 0.909816 View
ENSG00000091831 ESR1 ENSG00000179094 PER1 H. sapiens SSL Slorth 0.909661 View
ENSG00000091831 ESR1 ENSG00000114650 SCAP H. sapiens SSL Slorth 0.909649 View
ENSG00000091831 ESR1 ENSG00000176014 TUBB6 H. sapiens SSL Slorth 0.909626 View
ENSG00000091831 ESR1 ENSG00000197579 TOPORS H. sapiens SSL Slorth 0.909585 View
ENSG00000091831 ESR1 ENSG00000147647 DPYS H. sapiens SDL Slorth 0.909579 View
ENSG00000091831 ESR1 ENSG00000182504 CEP97 H. sapiens SDL Slorth 0.909529 View
ENSG00000091831 ESR1 ENSG00000127314 RAP1B H. sapiens SSL Slorth 0.909503 View
ENSG00000091831 ESR1 ENSG00000173402 DAG1 H. sapiens SSL Slorth 0.90941 View
ENSG00000091831 ESR1 ENSG00000167325 RRM1 H. sapiens SSL Slorth 0.909379 View
ENSG00000091831 ESR1 ENSG00000154237 LRRK1 H. sapiens SDL Slorth 0.909302 View
ENSG00000007255 TRAPPC6A ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.909196 View
ENSG00000091831 ESR1 ENSG00000198176 TFDP1 H. sapiens SSL Slorth 0.908962 View
ENSG00000091831 ESR1 ENSG00000149311 ATM H. sapiens SSL Slorth 0.908902 View