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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
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Experimentally Validated
Cancer:
Cancer gene:
Drug search:
Druggable:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
KEAP1
ENSG00000079999
H. sapiens
NSCLC
breast carcinoma
DIMETHYL FUMARATE
protein binding
transcription factor binding
ubiquitin-protein transferase activity
...
1476
RUNX1T1
ENSG00000079102
H. sapiens
AML
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
...
266
DLG1
ENSG00000075711
H. sapiens
guanylate kinase activity
phosphoprotein phosphatase activity
protein binding
...
530
SLC9A3R2
ENSG00000065054
H. sapiens
receptor binding
protein binding
beta-catenin binding
...
197
LRP6
ENSG00000070018
H. sapiens
low-density lipoprotein receptor activity
low-density lipoprotein receptor activity
receptor binding
...
87
TFRC
ENSG00000072274
H. sapiens
NHL
virus receptor activity
glycoprotein binding
double-stranded RNA binding
...
135
NDC80
ENSG00000080986
H. sapiens
structural constituent of cytoskeleton
protein binding
identical protein binding
...
535
TOP2B
ENSG00000077097
H. sapiens
ETOPOSIDE
TENIPOSIDE
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
...
1054
PPP2R2C
ENSG00000074211
H. sapiens
protein binding
protein phosphatase regulator activity
protein serine/threonine phosphatase activity
...
186
CLNS1A
ENSG00000074201
H. sapiens
protein binding
protein heterodimerization activity
...
265
XPO1
ENSG00000082898
H. sapiens
CLL
RNA binding
nuclear export signal receptor activity
transporter activity
...
2501
ACTL6B
ENSG00000077080
H. sapiens
transcription coactivator activity
structural constituent of cytoskeleton
...
81
UBE3C
ENSG00000009335
H. sapiens
ubiquitin-protein transferase activity
protein binding
...
51
POLR1A
ENSG00000068654
H. sapiens
DNA binding
chromatin binding
protein binding
...
222
THUMPD1
ENSG00000066654
H. sapiens
RNA binding
protein binding
...
197
RBL1
ENSG00000080839
H. sapiens
protein binding
transcription factor binding
promoter-specific chromatin binding
...
254
TMED2
ENSG00000086598
H. sapiens
protein binding
...
85
ORC1
ENSG00000085840
H. sapiens
DNA binding
chromatin binding
protein binding
...
1315
EPS15
ENSG00000085832
H. sapiens
ALL
calcium ion binding
protein binding
SH3 domain binding
...
1035
SPTLC1
ENSG00000090054
H. sapiens
serine C-palmitoyltransferase activity
protein binding
pyridoxal phosphate binding
...
39
SNAP23
ENSG00000092531
H. sapiens
SNAP receptor activity
protein binding
syntaxin binding
...
338
SUPT16H
ENSG00000092201
H. sapiens
protein binding
nucleosome binding
histone binding
...
1159
PXN
ENSG00000089159
H. sapiens
integrin binding
protein binding
beta-catenin binding
...
1608
ESR1
ENSG00000091831
H. sapiens
breast
BAZEDOXIFENE
DIENESTROL
DIETHYLSTILBESTROL
DIETHYLSTILBESTROL DIPHOSPHATE
ENCLOMIPHENE
ESTRADIOL
ESTRADIOL ACETATE
ESTRADIOL CYPIONATE
ESTRADIOL VALERATE
ESTROGENS, CONJUGATED
ESTROGENS, CONJUGATED SYNTHETIC A
ESTROGENS, ESTERIFIED
ESTRONE
ESTRONE SULFURIC ACID
ETHINYL ESTRADIOL
FULVESTRANT
MESTRANOL
OSPEMIFENE
POLYESTRADIOL PHOSPHATE
QUINESTROL
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B
TAMOXIFEN
TOREMIFENE
RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
...
4234
PKM
ENSG00000067225
H. sapiens
magnesium ion binding
pyruvate kinase activity
protein binding
...
154
NLK
ENSG00000087095
H. sapiens
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
...
399
CHMP5
ENSG00000086065
H. sapiens
protein binding
cadherin binding involved in cell-cell adhesion
...
251
EXOC5
ENSG00000070367
H. sapiens
protein binding
Ral GTPase binding
protein N-terminus binding
...
128
STRN4
ENSG00000090372
H. sapiens
protein binding
calmodulin binding
protein complex binding
...
374
PPP2R5C
ENSG00000078304
H. sapiens
protein binding
protein phosphatase regulator activity
...
227
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