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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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Experimentally Validated
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Cancer gene:
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Druggable:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
RIOK2
ENSG00000058729
H. sapiens
protein serine/threonine kinase activity
ATP binding
metal ion binding
...
1836
MAPK9
ENSG00000050748
H. sapiens
JUN kinase activity
protein binding
ATP binding
...
465
THOC3
ENSG00000051596
H. sapiens
RNA binding
...
99
MRTO4
ENSG00000053372
H. sapiens
protein binding
large ribosomal subunit rRNA binding
structural constituent of ribosome
...
421
RAD51
ENSG00000051180
H. sapiens
recombinase activity
four-way junction DNA binding
chromatin binding
...
669
GDI2
ENSG00000057608
H. sapiens
Rab GDP-dissociation inhibitor activity
GTPase activator activity
protein binding
...
210
PIAS1
ENSG00000033800
H. sapiens
DNA binding
transcription coactivator activity
transcription corepressor activity
...
285
HDAC7
ENSG00000061273
H. sapiens
BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
chromatin binding
transcription corepressor activity
protein kinase C binding
...
583
TRAPPC3
ENSG00000054116
H. sapiens
protein binding
...
262
ATP6V1H
ENSG00000047249
H. sapiens
protein binding
enzyme regulator activity
proton-transporting ATPase activity, rotational mechanism
...
271
EIF2AK2
ENSG00000055332
H. sapiens
double-stranded RNA binding
protein kinase activity
protein serine/threonine kinase activity
...
466
UQCRC1
ENSG00000010256
H. sapiens
metalloendopeptidase activity
ubiquinol-cytochrome-c reductase activity
zinc ion binding
...
52
CTNNA1
ENSG00000044115
H. sapiens
structural molecule activity
protein binding
beta-catenin binding
...
152
TNK2
ENSG00000061938
H. sapiens
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
...
1279
BCAR1
ENSG00000050820
H. sapiens
signal transducer activity
protein binding
SH3 domain binding
...
517
U2AF2
ENSG00000063244
H. sapiens
nucleotide binding
protein binding
poly-pyrimidine tract binding
...
882
WAPL
ENSG00000062650
H. sapiens
protein binding
molecular_function
...
284
GOPC
ENSG00000047932
H. sapiens
glioblastoma
cholangiocarcinoma
borderline ovarian
protein binding
ion channel binding
...
272
TPR
ENSG00000047410
H. sapiens
papillary thyroid
NSCLC
molecular_function
chromatin binding
mRNA binding
...
225
ZC3H15
ENSG00000065548
H. sapiens
protein binding
metal ion binding
cadherin binding involved in cell-cell adhesion
...
141
RHOA
ENSG00000067560
H. sapiens
diffuse gastric
T cell lymphomas
paediatric Burkitt lymphoma
GTPase activity
protein binding
GTP binding
...
2316
MAP2K4
ENSG00000065559
H. sapiens
pancreatic
breast
colorectal
protein kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
protein tyrosine kinase activity
...
579
VPS35
ENSG00000069329
H. sapiens
protein binding
protein transporter activity
D1 dopamine receptor binding
...
447
TRAPPC6A
ENSG00000007255
H. sapiens
protein binding
...
99
HDAC4
ENSG00000068024
H. sapiens
BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
RNA polymerase III transcription factor binding
core promoter binding
chromatin binding
...
727
NEDD4
ENSG00000069869
H. sapiens
protein binding
sodium channel inhibitor activity
protein domain specific binding
...
2515
UFD1L
ENSG00000070010
H. sapiens
thiol-dependent ubiquitin-specific protease activity
receptor binding
protein binding
...
3552
UBE2D1
ENSG00000072401
H. sapiens
ubiquitin-protein transferase activity
protein binding
ATP binding
...
1603
PRKACA
ENSG00000072062
H. sapiens
fibrolamellar hepatocellular carcinoma
cortisol secreting adrenal adenoma
protein serine/threonine kinase activity
cAMP-dependent protein kinase activity
protein serine/threonine/tyrosine kinase activity
...
1249
CDC42
ENSG00000070831
H. sapiens
GTPase activity
protein binding
GTP binding
...
2227
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