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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
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Experimentally Validated
Cancer:
Cancer gene:
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Druggable:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
PABPC1
ENSG00000070756
H. sapiens
HNSCC
biliary tract carcinoma
nucleotide binding
mRNA 3'-UTR binding
protein binding
...
1604
RAD18
ENSG00000070950
H. sapiens
Y-form DNA binding
damaged DNA binding
protein binding
...
820
ACTN1
ENSG00000072110
H. sapiens
double-stranded RNA binding
integrin binding
calcium ion binding
...
625
TAF11
ENSG00000064995
H. sapiens
DNA binding
transcription coactivator activity
protein binding
...
383
NCK2
ENSG00000071051
H. sapiens
SH3/SH2 adaptor activity
ARF guanyl-nucleotide exchange factor activity
protein binding
...
402
SREBF1
ENSG00000072310
H. sapiens
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
...
664
BCL3
ENSG00000069399
H. sapiens
CLL
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
...
531
RHOBTB1
ENSG00000072422
H. sapiens
GTP binding
...
210
TEAD2
ENSG00000074219
H. sapiens
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
...
237
WDR62
ENSG00000075702
H. sapiens
protein binding
...
13
PTPN23
ENSG00000076201
H. sapiens
protein tyrosine phosphatase activity
protein binding
protein kinase binding
...
90
ACTB
ENSG00000075624
H. sapiens
structural constituent of cytoskeleton
protein binding
ATP binding
...
2050
USP33
ENSG00000077254
H. sapiens
G-protein coupled receptor binding
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
...
199
MARK2
ENSG00000072518
H. sapiens
magnesium ion binding
protein serine/threonine kinase activity
protein binding
...
1402
THOC1
ENSG00000079134
H. sapiens
DNA binding
RNA binding
protein binding
...
494
UBE2K
ENSG00000078140
H. sapiens
ubiquitin-protein transferase activity
protein binding
ATP binding
...
3092
ITCH
ENSG00000078747
H. sapiens
ubiquitin-protein transferase activity
ubiquitin-protein transferase activity
protein binding
...
2187
RIMS1
ENSG00000079841
H. sapiens
protein binding
Rab GTPase binding
GTPase regulator activity
...
19
PSEN1
ENSG00000080815
H. sapiens
endopeptidase activity
aspartic-type endopeptidase activity
calcium channel activity
...
1957
STX7
ENSG00000079950
H. sapiens
SNARE binding
SNAP receptor activity
protein binding
...
320
PPP2R5A
ENSG00000066027
H. sapiens
protein binding
protein phosphatase regulator activity
kinase binding
...
204
MKNK1
ENSG00000079277
H. sapiens
protein serine/threonine kinase activity
calmodulin-dependent protein kinase activity
protein binding
...
219
ACAA1
ENSG00000060971
H. sapiens
acetyl-CoA C-acyltransferase activity
protein binding
acetate CoA-transferase activity
...
61
NSF
ENSG00000073969
H. sapiens
SNARE binding
SNARE binding
SNARE binding
...
456
MEF2A
ENSG00000068305
H. sapiens
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
...
279
SEL1L
ENSG00000071537
H. sapiens
protein binding
...
52
RPS6KA2
ENSG00000071242
H. sapiens
magnesium ion binding
protein serine/threonine kinase activity
ribosomal protein S6 kinase activity
...
290
TDP1
ENSG00000042088
H. sapiens
double-stranded DNA binding
single-stranded DNA binding
exonuclease activity
...
127
PRKCQ
ENSG00000065675
H. sapiens
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
...
153
CAMKK1
ENSG00000004660
H. sapiens
calmodulin-dependent protein kinase activity
protein binding
calmodulin binding
...
120
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