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Slorth
Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
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Experimentally Validated
Cancer:
Cancer gene:
Drug search:
Druggable:
Pathway:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
AP1M1
ENSG00000072958
H. sapiens
protein binding
...
181
HDAC9
ENSG00000048052
H. sapiens
BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
transcription corepressor activity
histone deacetylase activity
protein kinase C binding
...
226
FBXW11
ENSG00000072803
H. sapiens
ubiquitin-protein transferase activity
protein binding
protein dimerization activity
...
1082
CSNK2A2
ENSG00000070770
H. sapiens
protein serine/threonine kinase activity
protein binding
ATP binding
...
194
PUM3
ENSG00000080608
H. sapiens
DNA binding
mRNA binding
protein binding
...
158
REV3L
ENSG00000009413
H. sapiens
nucleotide binding
DNA binding
DNA-directed DNA polymerase activity
...
144
RAB7A
ENSG00000075785
H. sapiens
GTPase activity
protein binding
GTP binding
...
439
DDX1
ENSG00000079785
H. sapiens
DNA binding
chromatin binding
transcription cofactor activity
...
205
ACTR6
ENSG00000075089
H. sapiens
protein binding
...
387
SEC61A1
ENSG00000058262
H. sapiens
protein binding
transmembrane transporter activity
ribosome binding
...
154
DCUN1D1
ENSG00000043093
H. sapiens
protein binding
ubiquitin conjugating enzyme binding
ubiquitin-like protein binding
...
90
AP3D1
ENSG00000065000
H. sapiens
transporter activity
...
131
MLH1
ENSG00000076242
H. sapiens
colorectal
endometrial
ovarian
CNS tumours
CNS
chromatin binding
protein binding
ATP binding
...
369
VDAC3
ENSG00000078668
H. sapiens
nucleotide binding
voltage-gated anion channel activity
porin activity
...
131
UBE2A
ENSG00000077721
H. sapiens
ubiquitin-protein transferase activity
protein binding
ATP binding
...
735
PIAS2
ENSG00000078043
H. sapiens
DNA binding
transcription coactivator activity
protein binding
...
853
PSMA4
ENSG00000041357
H. sapiens
threonine-type endopeptidase activity
protein binding
...
1067
SENP1
ENSG00000079387
H. sapiens
endopeptidase activity
protein binding
SUMO-specific protease activity
...
256
FGFR1
ENSG00000077782
H. sapiens
MPN
NHL
salivary adenoma
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
REGORAFENIB
protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
...
723
SMARCE1
ENSG00000073584
H. sapiens
meningioma
chromatin binding
transcription coactivator activity
RNA binding
...
771
AMPH
ENSG00000078053
H. sapiens
ARF guanyl-nucleotide exchange factor activity
protein binding
phospholipid binding
...
44
NFKB2
ENSG00000077150
H. sapiens
B-NHL
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
...
269
NDUFS1
ENSG00000023228
H. sapiens
METFORMIN
protein binding
protein binding
NADH dehydrogenase (ubiquinone) activity
...
33
TRAF4
ENSG00000076604
H. sapiens
DNA binding
ubiquitin-protein transferase activity
tumor necrosis factor receptor binding
...
189
MARK3
ENSG00000075413
H. sapiens
protein serine/threonine kinase activity
protein binding
ATP binding
...
156
PER3
ENSG00000049246
H. sapiens
protein binding
kinase binding
ubiquitin protein ligase binding
...
207
SMARCA2
ENSG00000080503
H. sapiens
RNA polymerase II transcription coactivator activity
chromatin binding
transcription coactivator activity
...
1103
NOTCH3
ENSG00000074181
H. sapiens
receptor activity
calcium ion binding
protein binding
...
201
TSG101
ENSG00000074319
H. sapiens
DNA binding
transcription corepressor activity
protein binding
...
835
ACACB
ENSG00000076555
H. sapiens
acetyl-CoA carboxylase activity
biotin carboxylase activity
protein binding
...
351
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