TOP3A

ENSG00000177302 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003916 DNA topoisomerase activity
GO:0003917 DNA topoisomerase type I activity
GO:0005515 protein binding
GO:0008270 zinc ion binding

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
TOP3 S. cerevisiae
Top3alpha D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000149554 CHEK1 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.966097 View
ENSG00000177302 TOP3A ENSG00000197299 BLM H. sapiens SDL Slorth 0.965385 View
ENSG00000110107 PRPF19 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.965174 View
ENSG00000166851 PLK1 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.964377 View
ENSG00000112592 TBP ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.963462 View
ENSG00000175054 ATR ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.963393 View
ENSG00000175104 TRAF6 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.962965 View
ENSG00000087586 AURKA ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.962757 View
ENSG00000149311 ATM ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.962154 View
ENSG00000127445 PIN1 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.961165 View
ENSG00000166167 BTRC ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.960534 View
ENSG00000166949 SMAD3 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.958995 View
ENSG00000146648 EGFR ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.958549 View
ENSG00000077097 TOP2B ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.958501 View
ENSG00000116030 SUMO1 ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.957239 View
ENSG00000142208 AKT1 ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.956747 View
ENSG00000117748 RPA2 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.956687 View
ENSG00000158402 CDC25C ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.956434 View
ENSG00000177302 TOP3A ENSG00000197122 SRC H. sapiens SDL Slorth 0.955855 View
ENSG00000116478 HDAC1 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.955493 View
ENSG00000117399 CDC20 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.955451 View
ENSG00000177302 TOP3A ENSG00000187790 FANCM H. sapiens SDL Slorth 0.955114 View
ENSG00000135486 HNRNPA1 ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.953228 View
ENSG00000132155 RAF1 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.953201 View
ENSG00000087191 PSMC5 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.952705 View
ENSG00000139687 RB1 ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.952122 View
ENSG00000101266 CSNK2A1 ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.952045 View
ENSG00000174231 PRPF8 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.951835 View
ENSG00000005339 CREBBP ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.951255 View
ENSG00000055130 CUL1 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.950909 View
ENSG00000169083 AR ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.950165 View
ENSG00000131747 TOP2A ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.949397 View
ENSG00000012048 BRCA1 ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.94926 View
ENSG00000080824 HSP90AA1 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.949065 View
ENSG00000123374 CDK2 ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.948545 View
ENSG00000161057 PSMC2 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.948505 View
ENSG00000084774 CAD ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.948318 View
ENSG00000165280 VCP ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.947766 View
ENSG00000103275 UBE2I ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.946217 View
ENSG00000091831 ESR1 ENSG00000177302 TOP3A H. sapiens SDL Slorth 0.946179 View